Related Experiment Video
Updated: Jun 28, 2025
09:19
In Vitro Microfluidic Disease Model to Study Whole Blood-Endothelial Interactions and Blood Clot Dynamics in Real-Time
Published on: May 24, 2020
8.9K
COVID-19, thrombosis and pregnancy
Jahnavi Daru1, Katie White2, Beverley J Hunt2
1Institute for Population Health Science, Queen Mary University of London, London, UK.
Thrombosis Update
|April 15, 2024
Summary
Pregnant women with COVID-19 pneumonia face increased risks of thromboembolic events. Expert guidance now recommends increased thromboprophylaxis to improve maternal and infant outcomes.
Area of Science:
- Obstetrics and Gynecology
- Infectious Diseases
- Hematology
Background:
- COVID-19 pneumonia is associated with a higher incidence of thromboembolic events, particularly in critically ill patients.
- Pregnancy and the postpartum period are inherently prothrombotic states, increasing risks when combined with SARS-CoV-2 infection.
- Concerns exist regarding maternal and infant morbidity and mortality due to these combined risks.
Purpose of the Study:
- To review the impact of SARS-CoV-2 on national and international guidelines for preventing thromboembolic events in pregnant women.
- To highlight the importance of thromboprophylaxis in this high-risk population.
Main Methods:
- Review of current national and international expert-led guidance on COVID-19 and thromboembolism in pregnancy.
- Discussion of the rationale behind updated recommendations for thromboprophylaxis.
Main Results:
- The COVID-19 pandemic has prompted revisions in guidelines for managing thromboembolic risk in pregnant individuals.
- Increased use of thromboprophylaxis is a key recommendation in updated guidance.
Conclusions:
- Pregnant women require careful consideration for thromboembolic event prevention, especially when infected with SARS-CoV-2.
- Adherence to updated expert guidance on thromboprophylaxis is crucial for mitigating maternal and infant risks.
More Related Videos
05:31Author Spotlight: Modeling an Aspect of Preeclampsia in Female Mice Using Hypoxic Human Placenta-Derived Small Extracellular Vesicles
Published on: January 26, 2024
812
06:12Author Spotlight: A Novel Method for Comprehensive Cell Component Analysis of Cerebral Blood Clots
Published on: July 21, 2023
603
Related Concept Videos
01:30Anticoagulant Drugs: Low-Molecular-Weight Heparins
689
Hemostasis is a crucial process that prevents excessive blood loss from damaged blood vessels. It involves various mechanisms such as vasoconstriction, platelet adhesion and activation, and fibrin formation. The importance of each mechanism depends on the type of vessel injury. In contrast, thrombosis is the abnormal formation of a blood clot within the blood vessels, leading to potential complications if the clot obstructs blood flow. Thrombosis can be caused by increased coagulability of the...
689
01:24Disorders of Hemostasis
881
Hemostasis, the process that stops bleeding after a blood vessel injury, is crucial for maintaining the integrity of the circulatory system. However, disorders of hemostasis can disrupt this delicate balance, leading to either excessive clotting or bleeding. These disorders can be broadly classified into thromboembolic disorders and bleeding disorders.
Thromboembolic Disorders
Two factors primarily cause thromboembolic conditions.
Thromboembolic Disorders
Two factors primarily cause thromboembolic conditions.
881
01:07Teratogenicity
2.4K
The ability of a drug to produce structural deformations and functional abnormalities in the developing embryo or the fetus is called teratogenicity, and the drug producing this effect is known as a teratogen. Teratogenic effects include stillbirth, miscarriage, intrauterine growth restriction, and neurocognitive delay. A teratogen may affect the embryo at different stages of development, which is important in determining the type and extent of the damage. During blastocyst formation, the early...
2.4K
01:19Rh Blood Group
1.4K
The Rhesus (Rh) antigen is crucial in determining blood groups and ensuring compatibility during blood transfusions.
1.4K
01:26Sexually Transmitted Infections
304
Sexually transmitted infections (STIs) are diseases transmitted primarily through unsafe sexual interactions. Bacteria, viruses, or parasites cause them and can result in severe health complications if untreated.ChlamydiaThe bacterium Chlamydia trachomatis is responsible for the disease Chlamydia, the most common STI in the United States. This peculiar pathogen requires human cells to reproduce, residing intracellularly. The initial infection often goes unnoticed because it typically does not...
304
01:09Coagulation
6.4K
The coagulation phase is a critical part of the body's process to prevent blood loss following injury to blood vessels. It involves chemical reactions that form a clot to seal the injured area. The clotting process begins shortly after injury, within 15-20 seconds for severe damage and 1-2 minutes for minor injuries.
During the coagulation phase, clotting factors, or procoagulants, play a vital role in initiating and progressing the coagulation cascade. This cascade is a series of reactions...
During the coagulation phase, clotting factors, or procoagulants, play a vital role in initiating and progressing the coagulation cascade. This cascade is a series of reactions...
6.4K