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Surgically induced necrotizing scleritis (SINS): Is it a standalone condition or a variant of necrotizing scleritis?
Kowsigan Magesan1, Parthopratim Dutta Majumder1, Mamta Agarwal2
1Department of Uvea, Medical and Vision, Research Foundations, Sankara Nethralaya, Nungambakkam, Chennai, Tamil Nadu, India.
Purpose:
To report the clinical pattern of surgically induced necrotizing scleritis (SINS) in a tertiary eye care center in Southern India.
Methods:
Retrospective analysis of all SINS cases visiting the uveitis clinic of a tertiary eye institute between January 2009 and April 2019.
Results:
In total, 15 patients with a median age of 65 (IQR: 52-70) years were included in the study. Male (53%) predominance was noted, and SINS was unilateral (100%) in all cases. Most (87%) of the patients developed SINS after a single surgical procedure, with a median onset period of 251 (IQR: 127-1095) days. None of these patients had any evidence of systemic association. Ocular hypertension (n = 3, 20%), and cataract (n = 5, 33%) were the most common complications. When compared with a cohort of patients with idiopathic necrotizing scleritis, the index study did not find any statistically significant difference between SINS and idiopathic scleritis.
Conclusion:
SINS is idiopathic necrotizing scleritis rather than an independent entity of scleritis.

