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Published on: December 6, 2016
Nocturnal Urinary Symptoms as Screening Tools for Obstructive Sleep Apnea
Eliza F Burr1, Emily N B Myer, Jacqueline Y Kikuchi
1From the Division of Female Pelvic Medicine and Reconstructive Surgery, Department of Gynecology and Obstetrics, Johns Hopkins University School of Medicine, Baltimore, MD.
Nocturia (frequent nighttime urination) shows promise for screening obstructive sleep apnea (OSA) in urogynecology clinics. Nocturnal enuresis (bedwetting) was less effective for OSA screening.
Area of Science:
- Urogynecology
- Sleep Medicine
- Pulmonology
Background:
- Nocturnal lower urinary tract symptoms (LUTS) are associated with obstructive sleep apnea (OSA).
- Urogynecology clinics are potential sites for OSA screening due to routine LUTS assessment.
Purpose of the Study:
- To evaluate the accuracy of nocturia and nocturnal enuresis (NE) as screening tools for OSA in new patients at a urogynecology clinic.
- To determine the sensitivity and specificity of nocturia and NE for identifying OSA.
Main Methods:
- Retrospective study design analyzing data from women in a urogynecology clinic.
- Assessed diagnostic OSA testing, CPAP use, and LUTS improvement.
- Validated questionnaires were used for OSA screening.
- Polysomnography served as the gold standard for OSA diagnosis.
Main Results:
- Nocturia (≥2 episodes/night) demonstrated 86.4% sensitivity and 58.5% specificity for OSA screening (overall accuracy 78.4%).
- Nocturnal enuresis (≥1 episode/week) showed 31.8% sensitivity and 79.3% specificity (overall accuracy 56.1%).
Conclusions:
- Nocturia is a viable screening tool for OSA in urogynecology settings, with ≥2 episodes per night showing acceptable test characteristics.
- Nocturnal enuresis exhibited less favorable test characteristics for OSA screening.
- Urogynecology clinics can integrate nocturia assessment into clinical decision-making for OSA referral.
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