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Developing a Point-of-Care Molecular Test to Detect SARS-CoV-2
Debjani Paul1, Priyanka Naik1, Shomdutta Roy1
1Department of Biosciences and Bioengineering, Indian Institute of Technology Bombay, Powai, Mumbai 400076 India.
Transactions of the Indian National Academy of Engineering : an International Journal of Engineering and Technology
|April 16, 2024
Summary
Widespread COVID-19 testing in India is crucial. Researchers propose a novel paperfluidic molecular diagnostic test for point-of-care use, adaptable for future viral outbreaks.
Area of Science:
- Molecular Diagnostics
- Point-of-Care Testing
- Public Health
Background:
- The novel coronavirus (COVID-19) pandemic necessitates widespread testing in India.
- Current RT-PCR testing is limited by laboratory infrastructure, reagents, and trained personnel.
- Immunodiagnostic tests are not yet recommended for active infection diagnosis by the WHO.
Purpose of the Study:
- To address the need for accessible COVID-19 diagnostics in India.
- To develop a point-of-care molecular test for COVID-19 detection.
- To leverage paperfluidic technology for rapid molecular diagnostics.
Main Methods:
- Utilizing experience with paperfluidic devices for molecular diagnostics.
- Proposing the development of a novel diagnostic test for COVID-19.
- Adapting a platform technology for viral outbreak detection.
Main Results:
- The study proposes a new approach for COVID-19 diagnostics.
- The developed test aims for point-of-care application, overcoming current limitations.
- The platform technology shows potential for adaptability to future viral threats.
Conclusions:
- A paperfluidic-based molecular diagnostic test is proposed for COVID-19.
- This approach offers a potential solution for widespread, accessible testing.
- The technology can serve as a versatile platform for future infectious disease outbreaks.
