Cycloglycolurils: Hybrid Glycoluril-Cyclobenzil Macrocycles
Ashokkumar Basavarajappa1, Xiqu Wang1, Ognjen Š Miljanić1,2
1Department of Chemistry, University of Houston, Houston, Texas 77204-5003, United States.
Abstract:
Two novel glycoluril macrocycles have been synthesized from cyclotetrabenzil and cyclotribenzoin precursors using solvent-free condensations with urea. The crystal structure of the cyclotetra(p-phenylene)glycoluril macrocycle shows a twisted ring conformation, while that of the cyclotri(m-phenylene)glycoluril hybrid exhibits a distinct tubular supramolecular packing. These structures establish a potentially broad new class of macrocycles with intriguing guest binding properties owing to their available N-H motifs.
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