Related Experiment Video
Updated: Jun 28, 2025

06:51
A Patient-Derived Xenograft Model for Venous Malformation
Published on: June 15, 2020
5.3K
Head and Neck Vascular Anomalies in Children
Jeremy S Ruthberg1, Srinivas M Susarla2, Randall A Bly3
1Department of Otolaryngology-Head and Neck Surgery, University of Washington Medical Center, 1959 Northeast Pacific Street, UW Box 356515, Seattle, WA 98195, USA.
Oral and Maxillofacial Surgery Clinics of North America
|April 17, 2024
Summary
Craniomaxillofacial vascular anomalies, including tumors and malformations, require a multidisciplinary approach for pediatric patients. This review covers their causes, diagnosis, and management in the head and neck region.
Area of Science:
- Craniofacial medicine
- Pediatric vascular pathology
Background:
- Craniomaxillofacial vascular anomalies present diverse pathologies impacting pediatric patients.
- These conditions are classified as vascular tumors or vascular malformations based on biological and clinical factors.
- Significant functional and esthetic concerns necessitate specialized care.
Purpose of the Study:
- To review the etiology, clinical course, diagnosis, and management of craniomaxillofacial vascular anomalies.
- To highlight the importance of a multidisciplinary approach in optimizing outcomes for pediatric patients.
- To provide an overview of current therapeutic strategies for head and neck vascular anomalies.
Main Methods:
- Literature review of etiology, clinical presentation, diagnostic modalities, and treatment options.
- Synthesis of information on classification, biological properties, and distribution patterns.
- Analysis of multidisciplinary care models for complex pediatric cases.
Main Results:
- Craniomaxillofacial vascular anomalies are complex and varied, affecting pediatric patients significantly.
- Classification into tumors and malformations guides understanding of their behavior.
- Effective management relies on accurate diagnosis and tailored, often multidisciplinary, treatment plans.
Conclusions:
- A comprehensive understanding of craniomaxillofacial vascular anomalies is crucial for pediatric care.
- Multidisciplinary collaboration is essential for managing these complex conditions.
- Current practices focus on accurate diagnosis and tailored management to improve patient outcomes.
Related Concept Videos
Arteries of the Head and Neck
1.2K
The human body's intricate network of arteries ensures that every organ system receives the necessary oxygen and nutrients for optimal function. The arterial network in the head and neck region is particularly complex, providing vital blood flow to the brain, eyes, and other critical structures. Prominent arteries in this region include the internal carotid arteries and the vertebral arteries.
The internal carotid arteries supply blood to the anterior portion of the cerebrum. They enter the...
The internal carotid arteries supply blood to the anterior portion of the cerebrum. They enter the...
1.2K
Veins of Head and Neck
1.8K
The blood drainage from the head and neck is primarily managed by three pairs of veins: the external jugular, internal jugular, and vertebral veins. The external jugular veins drain superficial scalp and face structures, passing over the sternocleidomastoid muscles to empty into the subclavian veins.
On the other hand, the vertebral veins, unlike their arterial counterparts, are not primarily responsible for brain drainage. Instead, they drain the cervical vertebrae, spinal cord, and some small...
On the other hand, the vertebral veins, unlike their arterial counterparts, are not primarily responsible for brain drainage. Instead, they drain the cervical vertebrae, spinal cord, and some small...
1.8K
Overview of the Vascular System
2.8K
The vascular system comprises an extensive network of arteries, capillaries, and veins. The vascular system can be broadly divided into the blood and lymphatic systems. Typically, blood vessels can be categorized into three histological regions: tunica intima, tunica media, and tunica adventitia. The tunica intima consists of a single layer of endothelial cells attached to the basal lamina. Underlying the basal lamina is a connective tissue layer and an elastic lamina that gives stability and...
2.8K
Mechanism of Angiogenesis
5.4K
Blood vessel formation starts early during embryonic development, around day 7. In the extraembryonic yolk sac, mesodermal precursor cells called hemangioblast proliferate and differentiate into angioblast. Angioblasts express vascular endothelial growth factor receptor 2 or VEGFR2, which binds VEGF-A, a proangiogenic factor, guiding blood vessel formation. VEGF signaling promotes angioblasts to form a blood island in the developing embryo. Angioblasts further differentiate, giving rise to...
5.4K

