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Updated: Jun 28, 2025

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Burn Injury-Induced Pain and Depression-Like Behavior in Mice
Published on: September 29, 2021
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Gender differences in relation to stigmatization and depressive symptoms after burns
Elise Boersma-van Dam1, Inge Spronk2, Helma W C Hofland3
1Department of Clinical Psychology, Utrecht University, Utrecht, the Netherlands; Association of Dutch Burn Centres, Beverwijk, the Netherlands.
Summary
Gender moderates the impact of burn severity on mental health. Women show persistent links between surgeries and distress, while men
Area of Science:
- Psychology
- Burn Care
- Trauma Recovery
Background:
- Burn injuries significantly impact survivors' psychosocial well-being.
- Understanding long-term psychological adjustment after burns is crucial.
- Gender differences in coping with trauma are increasingly recognized.
Purpose of the Study:
- To examine the moderating role of gender in the relationship between burn severity, perceived stigmatization, and depressive symptoms.
- To investigate these relationships at multiple time points post-burn.
Main Methods:
- Multi-center study with two cohorts (N=215 longitudinal, N=180 cross-sectional).
- Measures included perceived stigmatization and depressive symptoms.
- Burn severity indicated by the number of acute surgeries.
- Gender-specific path models analyzed relationships and indirect effects.
Main Results:
- In both genders, more surgeries correlated with higher depressive symptoms and stigma at 3 months.
- Women showed a persistent direct link from surgeries to depressive symptoms and stigma at 12 months and 5-7 years.
- Men displayed bidirectional relationships between depressive symptoms and stigma from 3 to 12 months, with indirect effects from surgeries.
Conclusions:
- Burn severity impacts psychosocial adaptation differently in men and women.
- For women, burn severity remains a direct factor in psychological adjustment over time.
- For men, the influence of burn severity diminishes as depressive symptoms and stigma become interrelated over time.
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