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Updated: May 7, 2026

Chronic Salmonella Infected Mouse Model
Published on: May 31, 2010
Mycotic Aortic Aneurysm Secondary to Salmonella enterica Infection: A Case Report and Treatment Approach
Samah A Elshweikh1, Amr Abdellatif Ibrahim2, Waleed Saleh Almutairi3
1Internal Medicine/Hematology, Tanta University, Tanta, EGY.
Abstract:
Mycotic (infected) aortic aneurysm is a severe clinical condition with high morbidity and mortality. Salmonella spp. is a Gram-negative, rod-shaped bacteria that is typically limited to the gastrointestinal tract and resolves spontaneously but can progress to invasive infections such as bacteremia. Serious complications may arise, particularly in debilitated, elderly, and neonatal patients. We describe the case of a 74-year-old female with a history of diabetes and hypertension who presented with shortness of breath, fever, chills, abdominal pain, vomiting, and diarrhea. The patient's blood culture tested positive for Salmonella enterica, and she was given ceftriaxone based on the results, but he remained symptomatic. A computed tomography scan of the chest with contrast revealed a mycotic aneurysm of the thoracic aorta. The patient was urgently transferred to a higher level of care and underwent emergency thoracic endovascular aortic repair with stenting and intravenous antibiotics. The presence of an infected aneurysm and associated abscess formation in such high-risk patients makes the endovascular approach more suitable than other options such as open surgery, aneurysmal excision and ligation without arterial reconstruction, excision with immediate reconstruction, and excision with interval reconstruction.
Insights
Salmonella enterica bacteremia can lead to a rare but life-threatening mycotic thoracic aortic aneurysm. Endovascular repair with stenting offers a suitable treatment option for high-risk patients.
Area of Science:
- Cardiology
- Infectious Diseases
- Vascular Surgery
Background:
- Mycotic aortic aneurysms are rare but severe infections with high mortality.
- Salmonella spp. typically cause gastrointestinal infections but can lead to invasive disease, especially in vulnerable populations.
Observation:
- A 74-year-old female with diabetes and hypertension presented with sepsis secondary to Salmonella enterica bacteremia.
- Computed tomography revealed a mycotic aneurysm of the thoracic aorta, complicated by abscess formation.
Findings:
- Despite initial antibiotic treatment with ceftriaxone, the patient remained symptomatic.
- Emergency thoracic endovascular aortic repair with stenting was successfully performed.
Implications:
- Endovascular repair is a viable and potentially superior option for managing infected aortic aneurysms in high-risk patients compared to open surgery.
- This case highlights the importance of considering invasive Salmonella infections in patients with complex cardiovascular presentations.
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