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Updated: Jun 28, 2025

Analysis of Combinatorial miRNA Treatments to Regulate Cell Cycle and Angiogenesis
Published on: March 30, 2019
[Retracted] MicroRNA‑671‑5p inhibits cell proliferation, migration and invasion in non‑small cell lung cancer by
Junhui Ye1, Wujun Luo1, Lingling Luo1
1Department of Respiratory Medicine, The People's Hospital of Sanmen, Taizhou, Zhejiang 317100, P.R. China.
Abstract:
Following the publication of this paper, it was drawn to the Editors' attention by a concerned reader that the western blotting data shown in Fig. 4B and the Transwell cell invasion data shown in Figs. 2D and 4E were strikingly similar to data appearing in different form in other articles written by different authors at different research institutes that had already been published elsewhere prior to the submission of this paper to Molecular Medicine Reports (one of which has been retracted). Moreover, there appeared to be inappropriately edited western blot bands featured in Figs. 4 and 5. In view of the fact that certain of the abovementioned data had already apparently been published previously, the Editor of Molecular Medicine Reports has decided that this paper should be retracted from the Journal. After having been in contact with the authors, they agreed with the decision to retract the paper. The Editor apologizes to the readership for any inconvenience caused. [Molecular Medicine Reports 25: 30, 2022; DOI: 10.3892/mmr.2021.12546].
Insights
This study was retracted due to concerns about duplicated and manipulated western blotting and cell invasion data. The editors identified similarities to previously published work, leading to the paper's withdrawal.
Area of Science:
- Biomedical research integrity
- Scientific publishing ethics
- Data verification in molecular medicine
Context:
- Concerns raised by a reader regarding data duplication and manipulation.
- Similarities noted between presented western blotting and cell invasion data and previously published findings.
- Inconsistencies in western blot band editing were also identified.
Purpose:
- To address allegations of scientific misconduct.
- To evaluate the validity of the published data.
- To maintain the integrity of the scientific record.
Summary:
- The paper was retracted from Molecular Medicine Reports due to significant concerns about data integrity.
- Specifically, western blotting and Transwell cell invasion data showed striking similarities to previously published work.
- Inappropriately edited western blot bands were also identified, prompting retraction.
Impact:
- Retraction upholds scientific standards and protects the integrity of published research.
- Ensures accurate dissemination of scientific findings to the research community.
- Highlights the importance of rigorous peer review and post-publication scrutiny.
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