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Estimating Bilateral Atrial Function by Cardiovascular Magnetic Resonance Feature Tracking in Patients with Paroxysmal Atrial Fibrillation
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The Relationship of Coronary Thrombus Burden and Anticoagulation and Risk Factors in Atrial Fibrillation (ATRIA)

Gökhan Coşkun1, Cem Ozde1, Osman Kayapinar2

  • 1Düzce Üniversitesi Tip Fakültesi, Duzce, Turkey.

Clinical and Applied Thrombosis/Hemostasis : Official Journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis
|April 22, 2024
PubMed

Insights

The anticoagulation and risk factors in atrial fibrillation (ATRIA) score may predict high thrombus burden in ST-segment elevation myocardial infarction (STEMI) patients. Higher ATRIA scores indicate increased risk for significant coronary thrombus burden.

Area of Science:

  • Cardiology
  • Interventional Cardiology
  • Acute Coronary Syndromes

Background:

  • The anticoagulation and risk factors in atrial fibrillation (ATRIA) score is established for predicting adverse cardiovascular events.
  • The association between the ATRIA score and coronary thrombus burden in ST-segment elevation myocardial infarction (STEMI) patients remains unclear.

Purpose of the Study:

  • To investigate the relationship between the ATRIA score and thrombus burden in STEMI patients undergoing percutaneous coronary intervention (PCI).

Main Methods:

  • Prospective, cross-sectional observational study including 319 STEMI patients (January 2021 - April 2022).
  • Patients categorized into low thrombus burden (LTB, grade <3) and high thrombus burden (HTB, grade ≥3) groups.
  • ATRIA scores were calculated and compared between LTB and HTB groups.

Main Results:

  • The ATRIA risk score was significantly higher in the HTB group (p < .001).
  • Multivariate analysis identified ATRIA score, glomerular filtration rate, hypertension, abciximab usage, and no-reflow as independent predictors of HTB.
  • ATRIA score >4 predicted HTB with 66.2% sensitivity and 95.2% specificity; ATRIA score >8 predicted HTB with 98% sensitivity and 100% specificity.

Conclusions:

  • The ATRIA risk score is associated with thrombus burden in STEMI patients.
  • The ATRIA score may serve as a valuable predictor of high thrombus burden in STEMI patients undergoing PCI.
Abstract

Keywords:
ATRIA scoreST-segment elevation myocardial infarctionthrombus burden

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