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Survey of commercial antibodies targeting Y chromosome-encoded genes

Bradley D Gelfand1,2,3, Dionne A Argyle1,4, Joseph J Olivieri1,4

  • 1Center for Advanced Vision Science, University of Virginia School of Medicine, Charlottesville, Virginia, 22908, USA.

Medcomm - Future Medicine
|April 22, 2024
PubMed
Abstract

No abstract available in PubMed .

Keywords:
Y chromosomeantibody validationimmunoassay

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The Y chromosome is a sex chromosome found in several vertebrates and mammals, including humans. In addition to 22 pairs of autosomes, the human males have one X chromosome and one Y chromosome. In these organisms, the presence or absence of the Y chromosome determines the development of male traits.
Evolution
Around 300 million years ago, the two sex chromosomes diverged from two identical autosomal chromosomes. Over time, the Y chromosome has lost most of its genes, shrinking in size. Today,...