Spinal tumor embolization with Onyx: A systematic review and meta-analysis
Savio Batista1, Filipi Fim Andreão1, Marcelo Porto Sousa1
1Faculty of Medicine, Federal University of Rio de Janeiro, Rio De Janeiro, Brazil.
Summary
Onyx embolization for spinal tumors is safe, with no major complications or deaths reported in a systematic review. However, its efficacy requires further investigation due to limited and varied data.
Area of Science:
- Interventional Radiology
- Neurosurgery
- Oncology
Background:
- Onyx embolization is a promising technique for spinal tumors.
- It offers high devascularization rates and a low complication incidence.
Purpose of the Study:
- To evaluate the safety and efficacy of Onyx embolization in spinal tumor procedures.
- This systematic review and meta-analysis followed PRISMA guidelines.
Main Methods:
- Systematic review and meta-analysis of 11 articles (127 patients) reporting Onyx embolization outcomes for spinal tumors.
- Included outcomes: complications, mortality, blood loss, tumor devascularization, and tumor blush reduction.
Main Results:
- No major complications or deaths were reported.
- A low complication rate of 1% was observed, including one infarct and one vessel perforation.
- Complete tumor blush reduction in 52% of cases; median tumor devascularization of 91%.
Conclusions:
- Onyx embolization for spinal tumors demonstrates a safe profile with no major adverse events.
- Efficacy determination is challenging due to limited data and study heterogeneity.
- Further research is needed to validate findings and address knowledge gaps.
