Apomorphine has no effect on plasma homovanillic acid in schizophrenic patients

Previous experiments suggest that pharmacological perturbations of the brain dopaminergic system may be reflected by concentrations of plasma homovanillic acid. This study examined the ability of low-dose apomorphine to reduce plasma homovanillic acid concentrations in schizophrenic patients chronically treated with neuroleptics. The data suggest that apomorphine does not reduce plasma homovanillic acid in those patients.