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Updated: Jun 28, 2025

Hollow Microneedle-based Sensor for Multiplexed Transdermal Electrochemical Sensing

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Polymeric Microneedles for Health Care Monitoring: An Emerging Trend.

Raquel L Pereira¹, K B Vinayakumar¹, Sanna Sillankorva¹

¹INL - International Iberian Nanotechnology Laboratory, Av. Mestre José Veiga, 4715-330 Braga, Portugal.

|April 24, 2024

Summary

Polymeric microneedles offer a painless alternative to blood draws for bioanalyte collection. This review systematizes their diagnostic applications, safety, and market potential for future health monitoring.

Keywords:

analyte biomarkers bioreceptor biosensor healthcare interstitial fluid microneedle monitoring

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Last Updated: Jun 28, 2025

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Fabrication of Fine Electrodes on the Tip of Hypodermic Needle Using Photoresist Spray Coating and Flexible Photomask for Biomedical Applications

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Area of Science:

Biomedical Engineering
Medical Diagnostics
Materials Science

Background:

Traditional blood draws for bioanalyte collection are invasive, causing pain and needle phobia.
Microneedles offer a less invasive method by accessing interstitial fluid through the skin barrier.
Existing reviews primarily focus on microneedles for drug delivery, not diagnostics.

Purpose of the Study:

To systematically review the application of polymeric microneedles for diagnostic purposes.
To consolidate information on safety, clinical trials, and market distribution of diagnostic microneedles.
To project the future role of polymeric microneedles in health monitoring.

Main Methods:

Comprehensive literature search on polymeric microneedles for diagnostics.
Analysis of preclinical and clinical trial data.
Review of market trends and regulatory information.

Main Results:

Polymeric microneedles demonstrate potential as a safe and effective alternative for bioanalyte collection.
A growing body of evidence supports their use in diagnostic applications.
Information on safety, trials, and market access is crucial for clinical translation.

Conclusions:

Polymeric microneedles represent a promising technology for minimally invasive diagnostics.
Further research and clinical validation are needed to realize their full potential in health monitoring.
Systematization of data is key to advancing their adoption in healthcare.