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Updated: Jul 28, 2026

Annotation of Plant Gene Function via Combined Genomics, Metabolomics and Informatics
Published on: June 17, 2012
Studying Plant Specialized Metabolites Using Computational Metabolomics Strategies
Lana Mutabdžija1,2, Akhona Myoli3, Niek F de Jonge4
1Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences, Prague, Czechia.
None:
Plant specialized metabolites have diversified vastly over the course of plant evolution, and they are considered key players in complex interactions between plants and their environment. The chemical diversity of these metabolites has been widely explored and utilized in agriculture and crop enhancement, the food industry, and drug development, among other areas. However, the immensity of the plant metabolome can make its exploration challenging. Here we describe a protocol for exploring plant specialized metabolites that combines high-resolution mass spectrometry and computational metabolomics strategies, including molecular networking, identification of structural motifs, as well as prediction of chemical structures and metabolite classes.
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