Halogen-Bonding-Enabled Photoinduced Atom Transfer Radical Addition/Cyclization Reaction Leading to Tricyclic
Eiji Yamaguchi1,2, Masanobu Murai1, Akichika Itoh1,2
1Gifu Pharmaceutical University, 1-25-4, Daigaku-Nishi, Gifu 501-1196, Japan.
Abstract:
Atom transfer radical addition (ATRA) reactions are crucial for the dual functionalization of unsaturated hydrocarbons. Radical generation, pivotal in ATRA, has seen advancements from thermal to photochemical methods. Recent focus on halogen-bonding-based radical generation, including our group's innovative photochemical approach, offers cost-effective alternatives to transition-metal-dependent photocatalysts. This eliminates the need for high-energy UV light, enhancing the efficiency with noncovalent interactions.
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