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Updated: Jun 27, 2025

A Two-Step Protocol for Umpolung Functionalization of Ketones Via Enolonium Species
Published on: August 16, 2018
Electrochemical Oxidative Sulfonylation-Azidation of Alkenes
Bin Song1, Pengxiang Gao1, Bingcheng Hu1
1School of Chemical Engineering, Nanjing University of Science and Technology, Nanjing, Jiangsu 210094, China.
Abstract:
A novel electrochemical oxidative sulfonylation-azidation of alkenes is accomplished by using sulfonyl hydrazide and trimethylsilyl azide (TMSN3) for the one-pot and green synthesis of β-azidoarylsulfone, which involves the direct construction of new C-S and C-N bonds. Notably, neither exogenous oxidants/additives nor metal catalysts are required for this method. In addition, this electrochemical strategy features mild conditions and wide substrate scope and has been proved to be a radical pathway by mechanistic studies.
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