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Related Concept Videos

Long-term Depression01:05

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Long-term depression, or LTD, is one of the ways by which synaptic plasticity—changes in the strength of chemical synapses—can occur in the brain. LTD is the process of synaptic weakening that occurs over time between pre and postsynaptic neuronal connections. The synaptic weakening of LTD works in opposition to synaptic strengthening by long-term potentiation (LTP) and together are the main mechanisms that underlie learning and memory.
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Immersive Technologies for Depression Care: Scoping Review.

C Mahony Reategui-Rivera1, David Villarreal-Zegarra2,3, Kelly De La Cruz-Torralva4

  • 1Department of Biomedical Informatics, University of Utah, Salt Lake City, UT, United States.

JMIR Mental Health
|April 25, 2024
PubMed
Summary

Immersive technologies like virtual reality show promise for depression treatment, but research is limited. More studies are needed on diverse populations and therapeutic approaches to fully utilize these tools for mental health care.

Keywords:
augmented realitydepressionimmersive technologiesmobile phonevirtual reality

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Area of Science:

  • Mental Health Technology
  • Digital Therapeutics
  • Psychiatry

Background:

  • Depression affects 280 million globally, with a significant treatment gap as only 16.5% receive care.
  • Immersive technologies (IMTs), including virtual reality (VR) and augmented reality (AR), offer novel therapeutic avenues for depression.
  • Current evidence on the design, implementation, and use of IMTs for depression care remains limited.

Purpose of the Study:

  • To systematically map the existing evidence on immersive technology interventions for depression treatment.
  • To identify trends and gaps in the research landscape of IMTs in depression care.

Main Methods:

  • A scoping review methodology was employed to systematically search relevant databases.
  • The review focused on randomized clinical trials involving adult participants and the use of IMTs.
  • Multiple reviewers participated in study selection and data charting to ensure rigor and minimize bias.

Main Results:

  • 16 peer-reviewed articles were identified, with a majority originating from Europe (63%), particularly Poland (56%).
  • Studies predominantly utilized virtual reality (VR) (100%) via stand-alone headsets (88%), with interventions lasting 2-8 weeks, often in hospital settings (69%).
  • Ericksonian psychotherapy was the most common therapeutic approach (56%), yet few studies (13%) reported using VR design frameworks, and none mentioned implementation frameworks or barriers.

Conclusions:

  • There is a growing interest in utilizing IMTs, especially VR, for depression treatment, but research is not yet comprehensive.
  • Future research should prioritize inclusivity, explore diverse therapeutic modalities, and investigate cost-effectiveness.
  • Incorporating augmented reality (AR) and implementation science frameworks is crucial for advancing IMTs in mental health care.