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Related Concept Videos

Lethal Alleles02:41

Lethal Alleles

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Agouti: A Lethal Allele
Lucien Cuénot discovered lethal alleles in 1905 while studying the inheritance of coat color in mice. The agouti gene is responsible for the color of the coat in mice. This gene codes for an agouti-signaling protein, which is responsible for melanin distribution in mammals. The wild-type allele gives rise to gray-brown coat color in mice, while the mutant allele gives rise to yellow coat color. In addition to coat color, the agouti gene is associated with the yellow...
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Related Experiment Video

Updated: Jun 27, 2025

Cutaneous Leishmaniasis in the Dorsal Skin of Hamsters: a Useful Model for the Screening of Antileishmanial Drugs
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Lemmel's Syndrome: Lesson Based on a Case Report.

Renato Farina1, Pietro Valerio Foti1, Adriana Ilardi1

  • 1Department of Medical Surgical Sciences and Advanced Technologies "G.F. Ingrassia", University of Catania, Catania, Italy.

Journal of Medical Ultrasound
|April 26, 2024
PubMed
Summary

Lemmel's syndrome, a rare bile duct disease, involves nonobstructive jaundice caused by periampullary duodenal diverticula. Surgical removal of these diverticula is the recommended treatment to prevent complications.

Keywords:
Biliary ductsLemmel’s syndromecomputed tomographyduodenum diverticularesonance magnetic imagingultrasound

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Area of Science:

  • Gastroenterology
  • Hepatology
  • Biliary Medicine

Background:

  • Lemmel's syndrome is a rare condition characterized by bile duct disease.
  • It stems from periampullary duodenal diverticula located near the Vater papilla.

Observation:

  • This syndrome typically presents as nonobstructive jaundice.
  • Duodenal diverticula can cause biliary tract obstruction through extrinsic compression, leading to complications like lithiasis and cholangitis.

Findings:

  • Diagnosis is challenging, requiring correlation of recurrent biliary symptoms with duodenal diverticula compression.
  • Imaging studies reveal bile duct dilation without stones or pancreatic duct dilation, compressed by medial duodenal diverticula.

Implications:

  • Prompt diagnosis and surgical intervention (diverticulectomy) are crucial for managing Lemmel's syndrome.
  • Delayed diagnosis can lead to severe patient health complications.