Evaluation of contrast induced nephropathy related risk factors and long-term results

Area of Science:

• Cardiology
• Nephrology
• Radiology

Background:

• Contrast-induced nephropathy (CIN) is a significant concern following coronary angiography (CAG).
• Understanding CIN's incidence and risk factors is crucial for patient management.
• Long-term renal outcomes after CAG require further investigation.

Purpose of the Study:

• To determine the frequency of CIN in patients undergoing CAG.
• To identify established risk factors associated with CIN development.
• To assess the long-term renal outcomes in patients who experienced CIN post-CAG.

Main Methods:

• Retrospective evaluation of 934 patients who underwent CAG between April 2020 and April 2021.
• CIN defined by a characteristic increase in serum creatinine levels post-CAG.
• Analysis of patient data to correlate risk factors with CIN incidence and outcomes.

Main Results:

• CIN occurred in 5.4% (50/934) of patients.
• Higher CIN rates observed in patients with diabetes, hypertension, heart failure, and diuretic use.
• Pre-procedural hemoglobin, albumin, and GFR identified as independent risk factors for CIN.
• Patients with CIN exhibited significantly higher post-discharge urea and creatinine levels.

Conclusions:

• Pre-procedural evaluation of hemoglobin, albumin, and renal function is vital for CIN prevention.
• Maintaining normal hemoglobin and albumin levels may reduce CIN incidence.
• Proactive management of risk factors is essential for improving renal outcomes post-CAG.