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Updated: Jun 27, 2025
Hand-held Clinical Photoacoustic Imaging System for Real-time Non-invasive Small Animal Imaging
Published on: October 16, 2017
Near-Infrared Absorbing BODIPY-Xanthene Hybrids for Multiplexed Photoacoustic Imaging
Mohan Xu1, Qian Sun1,2, Xiaoqing Wang1
1College of Materials Science and Engineering, College of Science, Co-Innovation Center of Efficient Processing and Utilization of Forest Resources, Nanjing Forestry University, Nanjing 210037, People's Republic of China.
Abstract:
We report a series of ethenylene-bridged D-π-A BODIPY-xanthene hybrid dyes with precisely regulated absorption bands ranging from the far-red to the near-infrared region (NIR, 700-1000 nm) through rational molecular design. These dyes have excellent photoacoustic properties, and their biocompatibility can be significantly improved by facilely introducing water-soluble groups. In vivo two-channel multiplexed photoacoustic imaging demonstrated their high-resolution imaging capabilities, making them promising candidates for future NIR bioimaging applications.
