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Imaging in Rheumatic Immune-related Adverse Events
Jeremy Zhang1, Ruoning Ni2, Ibiyemi Oke2
1Department of Internal Medicine, University of Iowa Carver College of Medicine, 200 Hawkins Drive, C310 GH, Iowa City, IA 52242-1009, USA.
Abstract:
Since their introduction, immune checkpoint inhibitors have revolutionized cancer treatment by harnessing the body's own immune system as a defense against tumor growth. The downside of activating the immune system is the development of immune-related adverse events (irAEs), which mimic autoimmune disease of various organ systems. The musculoskeletal system is an uncommon, but substantial one for patients and can lead to long-term pain and disability that affects their quality of life. This review summarizes recent literature on imaging forms utilized for diagnosis and assessing treatment response in rheumatic irAEs.
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