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Chromogenic peptide substrate assays for determining components of the plasma kallikrein system
Abstract:
Methods for plasma prekallikrein, kallikrein like activity, kallikrein inhibitors and inhibitors of beta FXIIa using chromogenic peptide substrates are outlined. Results with these assays are described and discussed. Substrates for alpha and beta FXIIa are also described and the possibilities of a direct chromogenic substrate assay for FXII are discussed.