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Updated: Jun 27, 2025

An In Vitro 3D Model and Computational Pipeline to Quantify the Vasculogenic Potential of iPSC-Derived Endothelial Progenitors
Published on: May 13, 2019
Development of a 3D Vascular Network Visualization Platform for One-Dimensional Hemodynamic Simulation
Yan Chen1, Masaharu Kobayashi2, Changyoung Yuhn3
1Graduate School of Interdisciplinary Information Studies, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-0033, Japan.
Abstract:
Recent advancements in computational performance and medical simulation technology have made significant strides, particularly in predictive diagnosis. This study focuses on the blood flow simulation reduced-order models, which provide swift and cost-effective solutions for complex vascular systems, positioning them as practical alternatives to 3D simulations in resource-limited medical settings. The paper introduces a visualization platform for patient-specific and image-based 1D-0D simulations. This platform covers the entire workflow, from modeling to dynamic 3D visualization of simulation results. Two case studies on, respectively, carotid stenosis and arterial remodeling demonstrate its utility in blood flow simulation applications.

