Post-surgical Persistent Hyperparathyroidism Successfully Treated with Parathyroid Radiofrequency Ablation: A Case...

Area of Science:

• Endocrinology
• Minimally Invasive Procedures
• Surgical Oncology

Background:

• Primary hyperparathyroidism (PHPT) is typically managed with parathyroidectomy, a procedure associated with potential complications and recurrence.
• Minimally invasive techniques like Microwave Ablation (MWA) and Radiofrequency Ablation (RFA) are emerging alternatives for specific PHPT patient cohorts.

Observation:

• A 54-year-old woman with persistent PHPT post-parathyroidectomy presented with left parathyroid hyperplasia.
• Diagnostic imaging, including ultrasound and 99mTc-MIBI scintigraphy, guided the treatment approach.

Findings:

• Radiofrequency ablation (RFA) was successfully employed to treat the persistent parathyroid hyperplasia.
• The patient achieved remission of PHPT, confirmed by normalized blood tests 7 months post-RFA treatment.

Implications:

• RFA presents a viable minimally invasive option for PHPT, particularly for patients with increased surgical risks.
• Further research is warranted to establish RFA as a potential first-line therapy for PHPT.