Related Experiment Video
Updated: Jun 27, 2025

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Generation and Culturing of High-Grade Serous Ovarian Cancer Patient-Derived Organoids
Published on: January 6, 2023
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Patient-Derived Xenograft Models for Ovarian Cancer
Trang Minh Tran1,2, Gwo Yaw Ho2,3, Simon Chu4
1Hudson Institute of Medical Research, Clayton, VIC, Australia.
Methods in Molecular Biology (Clifton, N.J.)
|April 27, 2024
Abstract
None:
Patient-derived xenograft (PDX) models play a crucial role for in vivo research. They maintain the original molecular characteristics of the human tumor and provide a more accurate tumor microenvironment, which cannot be replicated by in vitro models. This chapter describes four different transplantation methods, namely, intra-bursal, intrarenal capsule, intraperitoneal, and subcutaneous, to develop PDX models for ovarian cancer research.

