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Pityriasis lichenoides: assessment of 41 pediatric patients

Aluhine L Fatturi1, Mariana A P Morgan1, Jandrei R Markus1

  • 1Pediatric Dermatology Division, Department of Pediatrics, Federal University of Paraná, UFPR, Curitiba, Brazil.

Jornal De Pediatria
|April 27, 2024
PubMed

Insights

Pityriasis lichenoides chronica (PLC) was most common in school-aged children and adolescents. Phototherapy showed higher remission rates than antibiotics for this pediatric skin condition.

Area of Science:

  • Pediatric Dermatology
  • Dermatology
  • Clinical Research

Background:

  • Pityriasis lichenoides (PL) is a rare skin condition affecting children.
  • Understanding its characteristics and treatment outcomes is crucial for effective management.

Purpose of the Study:

  • To evaluate the clinical features and treatment responses of pediatric patients with pityriasis lichenoides over 43 years.
  • To identify factors influencing remission rates in this population.

Main Methods:

  • Retrospective, analytical, longitudinal study of pediatric patients (<15 years).
  • Analysis of medical records, including demographics, clinical forms (PLC, PLEVA), and treatment outcomes.
  • Statistical analysis using t-tests, chi-square tests, and logistic regression (p < 0.05).

Main Results:

  • 41 pediatric patients diagnosed with pityriasis lichenoides (78% PLC, 12.2% PLEVA).
  • Two incidence peaks observed (2004-2006 and 2019-2021), potentially linked to infectious outbreaks.
  • Overall remission rate of 71.9%; phototherapy (80% remission) showed higher efficacy than antibiotic therapy (56.6% remission).
  • Disease onset after age 5 significantly increased the likelihood of remission (13 times greater).

Conclusions:

  • Pityriasis lichenoides chronica is the predominant form in pediatric patients, particularly school-aged children and adolescents.
  • Treatment with phototherapy demonstrated superior remission rates compared to antibiotic therapy.
  • Delayed onset of pityriasis lichenoides (after age 5) is associated with a better prognosis for remission.
Abstract

Keywords:
ChildClinical diagnosisPityriasis lichenoidesTreatment

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