Related Experiment Video
Updated: May 10, 2026

Surgical Swine Model of Chronic Cardiac Ischemia Treated by Off-Pump Coronary Artery Bypass Graft Surgery
Published on: March 27, 2018
The Current State of Hybrid Coronary Revascularization
Robin Willard1, Joshua Scheinerman2, Stevan Pupovac3
1Department of Cardiovascular & Thoracic Surgery, Lenox Hill Hospital/Northwell Health, New York, New York.
Insights
Hybrid coronary revascularization (HCR) offers comparable survival to bypass surgery with better resource use and less short-term illness. It may also reduce repeat procedures compared to percutaneous coronary intervention (PCI).
Area of Science:
- Cardiology
- Cardiovascular Surgery
- Interventional Cardiology
Background:
- Hybrid coronary revascularization (HCR) integrates minimally invasive surgery and percutaneous coronary intervention (PCI) for multivessel coronary artery disease.
- Widespread adoption of HCR remains limited despite its established use.
- Comparative analysis of HCR against traditional coronary artery bypass graft (CABG) surgery and multivessel PCI is crucial.
Purpose of the Study:
- To comparatively assess Hybrid coronary revascularization (HCR) against traditional coronary artery bypass graft (CABG) surgery and multivessel percutaneous coronary intervention (PCI).
- To evaluate the efficacy, safety, and resource utilization of HCR in treating multivessel coronary artery disease.
Main Methods:
- Review of existing studies comparing HCR with CABG and multivessel PCI.
- Analysis of data on resource utilization, short-term morbidity, and mid- to long-term survival.
- Assessment of periprocedural morbidity and the need for repeat revascularization.
Main Results:
- HCR demonstrates comparable mid- and long-term survival to traditional CABG.
- HCR may offer advantages in resource utilization and short-term morbidity compared to CABG.
- HCR shows similar periprocedural morbidity to PCI but potentially reduces repeat revascularization through surgical arterial grafts.
Conclusions:
- HCR presents a viable alternative for multivessel coronary artery disease, balancing benefits of surgical and interventional approaches.
- Further large-scale randomized trials are needed to solidify HCR's position in clinical practice.
- HCR may optimize treatment strategies by combining the durability of arterial grafts with the precision of PCI.
Abstract:
Hybrid coronary revascularization (HCR) combines a minimally invasive surgical approach with percutaneous coronary intervention (PCI) for the treatment of multivessel coronary artery disease. Despite decades of use, widespread acceptance has been limited. In this review, we conduct a comparative assessment of HCR in relation to traditional coronary artery bypass graft surgery and multivessel PCI. Although large-scale randomized data are still lacking, numerous studies have demonstrated that HCR may offer benefits regarding resource utilization and short-term morbidity while delivering comparable mid- and long-term survival compared with traditional bypass surgery. Compared with PCI, HCR may offer similar periprocedural morbidity while mitigating the need for repeat revascularization by providing a surgical arterial bypass graft to the left anterior descending artery.
Related Concept Videos
Ischemic Heart Disease: Overview
Atherosclerosis, the primary malefactor, orchestrates this dangerous condition. It manifests as the accumulation of fatty deposits, akin to insidious plaques, within arterial walls. As time elapses, these plaques metamorphose, hardening and narrowing...
Cardiac Catheterization I: Pre-Procedure Overview
Coronary Artery Disease V: Interprofessional Care
Acute Coronary Syndrome I: Introduction
Acute Coronary Syndrome III: Diagnostic Studies
Acute Coronary Syndrome IV: Interprofessional Care

