Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Overlap in parasite communities among vervet monkeys, humans, livestock and dogs at Lake Nabugabo, Uganda.

Parasitology·2026

Same author

Shifts in strongylid communities associated with chronic wasting in mountain gorillas.

International journal for parasitology·2026

Same author

Strongyloides Genetic Diversity among Humans, Dogs, and Nonhuman Primates, Central African Republic, 2016-2022.

Emerging infectious diseases·2026

Same author

Hookworm genes encoding intestinal excreted-secreted proteins are transcriptionally upregulated in response to the host's immune system.

PLoS neglected tropical diseases·2026

Same author

Developmental plasticity enables an intestinal tapeworm to adapt to dietary stress.

Nature communications·2026

Same author

The potential threat of Strongyloides spp. to mountain gorillas and public health in Bwindi Impenetrable National Park, Uganda.

Parasitology research·2026

Same journal

The second Cryptosporidium meeting: Edinburgh's parasite deep dive.

Trends in parasitology·2026

Same journal

Evolution of generalism under Muller's ratchet.

Trends in parasitology·2026

Same journal

Next generation in parasitology 2026: Connecting young parasitologists across Europe.

Trends in parasitology·2026

Same journal

Disrupted barriers, evolved risks: toward precision One Health in arthropod allergy.

Trends in parasitology·2026

Same journal

Unveiling malaria history using ancient genomes.

Trends in parasitology·2026

Same journal

Tuft cells awaken Th2 recall responses.

Trends in parasitology·2026

See all related articles

Search research articles

Related Experiment Video

Updated: Jun 27, 2025

Generating Transgenics and Knockouts in Strongyloides Species by Microinjection

Generating Transgenics and Knockouts in Strongyloides Species by Microinjection

Published on: October 7, 2021

Hookworm genomics: dusk or dawn?

Vladislav Ilík¹, Erich M Schwarz², Eva Nosková¹

¹Institute of Vertebrate Biology, Czech Academy of Sciences, Brno, Czech Republic; Department of Botany and Zoology, Faculty of Science, Masaryk University, Brno, Czech Republic.

Trends in Parasitology

|April 27, 2024

Summary

This summary is machine-generated.

Genomic data for most hookworm species, especially those infecting wildlife, is lacking. Assembling genomes from single hookworms offers a promising new avenue for research on these neglected parasitic nematodes.

Keywords:

Ancylostoma Necator genome genomics hookworms sequencing

More Related Videos

Using Single-Worm Data to Quantify Heterogeneity in Caenorhabditis elegans-Bacterial Interactions

Using Single-Worm Data to Quantify Heterogeneity in Caenorhabditis elegans-Bacterial Interactions

Published on: July 22, 2022

Small-Scale Extraction of Caenorhabditis elegans Genomic DNA

Small-Scale Extraction of Caenorhabditis elegans Genomic DNA

Published on: June 7, 2022

Related Experiment Videos

Last Updated: Jun 27, 2025

Generating Transgenics and Knockouts in Strongyloides Species by Microinjection

Generating Transgenics and Knockouts in Strongyloides Species by Microinjection

Published on: October 7, 2021

Using Single-Worm Data to Quantify Heterogeneity in Caenorhabditis elegans-Bacterial Interactions

Using Single-Worm Data to Quantify Heterogeneity in Caenorhabditis elegans-Bacterial Interactions

Published on: July 22, 2022

Small-Scale Extraction of Caenorhabditis elegans Genomic DNA

Small-Scale Extraction of Caenorhabditis elegans Genomic DNA

Published on: June 7, 2022

Area of Science:

Parasitology
Genomics
Nematology

Background:

Hookworms are significant global health and economic burdens.
Only a fraction of known hookworm species have available genetic or genomic data.
Existing genomic data is outdated, hindering current research.

Purpose of the Study:

To summarize the current state of hookworm genomics.
To highlight challenges in obtaining genomic data for hookworms.
To identify opportunities for advancing hookworm research through genomics.

Main Methods:

Review of existing literature on hookworm genetics and genomics.
Analysis of current gaps in genomic data availability.
Discussion of emerging techniques for genome assembly.

Main Results:

Limited genomic data exists for only a few hookworm species, with 96 species lacking any genomic information.
The majority of hookworm diversity, particularly in wildlife hosts, remains unsequenced.
Recent advancements suggest single-worm genome assembly is a viable approach.

Conclusions:

Significant gaps exist in genomic data for hookworm species, particularly those of wildlife.
Single-worm genome assembly presents a critical opportunity to expand genomic resources.
Further research is needed to overcome challenges and harness the potential of hookworm genomics.