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09:02
A Large Animal Model for Acute Kidney Injury by Temporary Bilateral Renal Artery Occlusion
Published on: February 2, 2021
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Acute Kidney Injury After Percutaneous Coronary Intervention Guided by Intravascular Ultrasound
Minh Tran Duc1, Thai Nguyen Quoc2, Bach Yen T Nguyen1
1Cardiology, Tam Anh Hospital, Ha Noi, VNM.
Cureus
|April 29, 2024
Summary
Intravascular ultrasound guidance significantly reduces contrast-induced acute kidney injury (CI-AKI) in patients undergoing percutaneous coronary intervention (PCI). This imaging technique offers a safer alternative to angiography alone, especially for high-risk patients.
Area of Science:
- Cardiology
- Nephrology
- Medical Imaging
Background:
- Contrast-induced acute kidney injury (CI-AKI) is a significant complication following percutaneous coronary intervention (PCI).
- Angiography guidance in PCI may lead to higher contrast volumes and increased risk of CI-AKI.
- Intravascular ultrasound (IVUS) offers detailed real-time imaging during PCI procedures.
Purpose of the Study:
- To evaluate the effectiveness of intravascular ultrasound (IVUS) guidance in reducing CI-AKI incidence compared to traditional angiography guidance.
- To assess the safety and impact of IVUS on contrast volume administration during PCI.
Main Methods:
- A prospective cohort study involving 99 patients undergoing PCI at Vietnam National Heart Institute - Bach Mai Hospital.
- Patients were divided into two groups: IVUS-guided PCI (33 patients) and angiography-guided PCI (66 patients).
- The primary endpoint was the incidence of acute kidney injury during hospitalization.
Main Results:
- The IVUS-guided group used significantly less contrast volume (95.2 ± 37.1 mL) compared to the angiography-guided group (133.0 ± 36.0 mL) (P < 0.0001).
- The incidence of CI-AKI was significantly lower in the IVUS-guided group (0.0%) compared to the angiography-guided group (12.12%) (P = 0.049).
Conclusions:
- Intravascular ultrasound (IVUS) is a safe and effective imaging tool for guiding percutaneous coronary intervention (PCI).
- IVUS guidance significantly reduces the incidence of contrast-induced acute kidney injury (CI-AKI) compared to angiography alone.
- Patients at high risk for CI-AKI may particularly benefit from IVUS-guided PCI.
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