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Updated: Jun 27, 2025
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An Intestinal Gut Organ Culture System for Analyzing Host-Microbiota Interactions
Published on: June 30, 2021
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Probiotics: Shaping the gut immunological responses.
Eirini Filidou1, Leonidas Kandilogiannakis1, Anne Shrewsbury2
1Faculty of Medicine, Laboratory of Pharmacology, Democritus University of Thrace, Alexandroupolis 68100, Greece.
World Journal of Gastroenterology
|April 29, 2024
Summary
Probiotics, beneficial live microorganisms, improve gut health and immune responses. Recent studies highlight their role in managing intestinal inflammation and supporting gut microbiota, offering therapeutic potential for inflammatory bowel diseases (IBD).
Area of Science:
- Microbiology
- Immunology
- Gastroenterology
Background:
- Probiotics are live microorganisms conferring health benefits.
- Lactobacillaceae, Bifidobacteriaceae, and yeasts are well-studied probiotics.
- Intestinal inflammation, common in IBD, involves microbiota imbalance and mucosal damage.
Conclusions:
- Probiotics and their metabolites (postbiotics) positively influence gut health and immunity.
- Despite controversial clinical results in IBD, their beneficial effects are evident.
- Specific probiotic genera show promise in combating intestinal inflammation.
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