Related Experiment Video

Updated: Jun 27, 2025

Malachite Green Assay for the Discovery of Heat-Shock Protein 90 Inhibitors
07:57

Malachite Green Assay for the Discovery of Heat-Shock Protein 90 Inhibitors

Published on: January 20, 2023

5.3K

Editor's Note: Antiangiogenic Properties of 17-(Dimethylaminoethylamino)-17-Demethoxygeldanamycin: An Orally

Gurmeet Kaur, Dorina Belotti, Angelika M Burger

    Clinical Cancer Research : an Official Journal of the American Association for Cancer Research
    |May 1, 2024
    PubMed
    Abstract

    No abstract available in PubMed .

    More Related Videos

    Ex Vivo Treatment Response of Primary Tumors and/or Associated Metastases for Preclinical and Clinical Development of Therapeutics
    08:29

    Ex Vivo Treatment Response of Primary Tumors and/or Associated Metastases for Preclinical and Clinical Development of Therapeutics

    Published on: October 2, 2014

    14.8K
    Intracellular Refolding Assay
    07:18

    Intracellular Refolding Assay

    Published on: January 24, 2012

    14.2K

    Related Experiment Videos

    Last Updated: Jun 27, 2025

    Malachite Green Assay for the Discovery of Heat-Shock Protein 90 Inhibitors
    07:57

    Malachite Green Assay for the Discovery of Heat-Shock Protein 90 Inhibitors

    Published on: January 20, 2023

    5.3K
    Ex Vivo Treatment Response of Primary Tumors and/or Associated Metastases for Preclinical and Clinical Development of Therapeutics
    08:29

    Ex Vivo Treatment Response of Primary Tumors and/or Associated Metastases for Preclinical and Clinical Development of Therapeutics

    Published on: October 2, 2014

    14.8K
    Intracellular Refolding Assay
    07:18

    Intracellular Refolding Assay

    Published on: January 24, 2012

    14.2K

    Related Concept Videos

    Regulation of Angiogenesis and Blood Supply01:24

    Regulation of Angiogenesis and Blood Supply

    2.6K
    Rapidly dividing tumors, embryos, and wounded tissues require more oxygen than usual, lowering the oxygen concentration in the blood. At low oxygen or hypoxic conditions, an oxygen-sensitive transcription factor called the hypoxia-inducible factor 1 or HIF1 is activated. HIF1 is a dimeric protein of alpha (ɑ) and beta (β) subunits.  Under optimal oxygen conditions, HIF1β is present in the nucleus while HIF1ɑ remains in the cytosol. HIF1ɑ is hydroxylated by prolyl...
    2.6K

    Articles linked to this work by shared authors, journal, and citation graph.

    Macrocyclic peptides and peptidomimetics as modulators of protein-protein interactions.

    RSC medicinal chemistry·2026

    Millet Consumption Patterns, Perceptions, and Barriers among Non-Communicable Disease Patients in an Urban Resettlement Colony of Delhi: A Mixed-Methods Study.

    Indian journal of community medicine : official publication of Indian Association of Preventive & Social Medicine·2026

    Leveraging molecular dynamics to unravel the inhibition mechanism of potential β-secretase (BACE1) inhibitors.

    Physical chemistry chemical physics : PCCP·2026

    KRAS-mediated CCDC6 degradation drives xCT upregulation and ferroptosis evasion.

    Apoptosis : an international journal on programmed cell death·2026

    Design and Implementation of an Automated Interpretation Algorithm for Lupus Anticoagulant Functional Testing.

    International journal of laboratory hematology·2026

    Neural stem cell delivery of oncolytic CRAd-S-pk7 immunotherapy for stage 3 ovarian cancer: Dose-regimen studies.

    Molecular therapy. Oncology·2026

    Lessons from Cohort Studies of Targetable Metabolic Deficiencies in Lung Cancer.

    Clinical cancer research : an official journal of the American Association for Cancer Research·2026

    KRAS Q61 NSCLC: When Alleles Matter.

    Clinical cancer research : an official journal of the American Association for Cancer Research·2026

    Target Antigen Identification for Antibody Drug Conjugate Therapy in Biliary Tract Cancer.

    Clinical cancer research : an official journal of the American Association for Cancer Research·2026

    Response-Adapted Surgery after Neoadjuvant Immunochemotherapy in Locally Advanced Head and Neck Squamous Cell Carcinoma (REMATCH): A Single-Arm Phase II Trial.

    Clinical cancer research : an official journal of the American Association for Cancer Research·2026

    Associations of Baseline Neutrophil-to-Lymphocyte Ratio with Efficacy and Toxicity of the B7H3 ADC YL201, Linked to Interleukin-6: Analysis of the Phase 1/1b Trial.

    Clinical cancer research : an official journal of the American Association for Cancer Research·2026

    Ceralasertib plus durvalumab in Ras mutant and Ras wild type advanced non-small cell lung cancer: Two cohorts of the phase II platform National Lung Matrix Trial.

    Clinical cancer research : an official journal of the American Association for Cancer Research·2026

    Chemical components with antitumour activity from Inula britannica.

    Phytochemistry·2026

    Diallyl sulfide pretreatment protects against DSS-induced colitis by reshaping the gut microbiota and enhancing microbiota-associated tryptophan metabolism.

    Journal of ethnopharmacology·2026

    (S)-SA, a bioactive flavonoid from Dalbergiae Odoriferae Lignum, alleviates cerebral ischemia-reperfusion injury via SLC11A2-mediated ferroptosis inhibition.

    Phytomedicine : international journal of phytotherapy and phytopharmacology·2026

    Balancing efficacy and risk: A toxicological review and safety transformation of Berberis plants and their alkaloids.

    Phytomedicine : international journal of phytotherapy and phytopharmacology·2026

    Experimental and theoretical approaches on structural, electronic, thermal and conductivity properties of ethynylated versus alkoxylated chalcones and elucidation of their cytotoxicity mechanisms in Acanthamoeba cells.

    Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy·2026

    New phenolic derivatives and bioactive constituents from Castanopsis lamontii Hance: enzyme inhibitory activities and structure-activity insights.

    Natural product research·2026
    See all related articles
    JoVE
    x logofacebook logolinkedin logoyoutube logo
    ABOUT JoVE
    OverviewLeadershipBlogJoVE Help Center
    AUTHORS
    Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
    LIBRARIANS
    TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
    RESEARCH
    JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
    EDUCATION
    JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
    Terms & Conditions of Use
    Privacy Policy
    Policies
    Jove
    Visualize
    Contact Us