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[Malaria vaccines: a new tool for elimination?]
Blaise Genton1, Valérie D'Acremont1
1Policlinique de médecine tropicale, voyages et vaccinations, Centre universitaire de médecine générale et santé publique, Unisanté, 1011 Lausanne.
Two malaria vaccines are now recommended by the WHO for children in endemic areas. These vaccines offer partial protection against malaria, complementing other control measures.
Area of Science:
- Global Health
- Vaccinology
- Parasitology
Context:
- Malaria cases are stagnating or increasing globally.
- Emerging insecticide resistance, conflicts, and climate change exacerbate malaria.
- WHO recommends malaria vaccines for children in high-transmission areas.
Purpose:
- To summarize the current status and recommendations for malaria vaccines.
- To highlight the role of vaccines alongside other malaria control strategies.
Summary:
- The RTS,S/ASO1 malaria vaccine was recommended by WHO in 2021 for children aged 5-17 months.
- A second malaria vaccine was approved in 2023, showing approximately 70% efficacy in young children for one year.
- These vaccines are complementary tools to combat rising malaria cases.
Impact:
- Vaccine deployment aims to curb malaria stagnation and increase.
- Partial efficacy necessitates continued use of other preventive measures.
- Current vaccines are not recommended for travelers due to limited efficacy.
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