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Related Concept Videos

Diabetes: Management and Pharmacotherapy01:15

Diabetes: Management and Pharmacotherapy

268
The therapy for diabetes aims to alleviate hyperglycemia-related symptoms, prevent acute metabolic decompensation, and reduce chronic end-organ complications. Glycemic control is evaluated through short-term (self-monitoring, continuous glucose monitoring) and long-term (A1c, fructosamine) metrics, enabling near real-time tracking of blood glucose levels and reflecting glycemic control over specific time frames.
Insulin remains the cornerstone of treatment for most patients with type 1 and many...
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Diabetes: Symptoms, Diagnosis, and Complications01:15

Diabetes: Symptoms, Diagnosis, and Complications

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For most patients, experiencing several weeks of polyuria, polydipsia, fatigue, and significant weight loss may indicate the presence of diabetes. Furthermore, adults displaying the phenotypic appearance of type 2 diabetes (particularly those who are obese and not initially insulin-requiring), may have islet cell autoantibodies, suggesting autoimmune-mediated β cell destruction and a diagnosis of latent autoimmune diabetes of adults (LADA). The categorization of glucose homeostasis is...
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Dialysis01:27

Dialysis

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Renal failure occurs when the kidneys lose their ability to filter waste products from the blood effectively. It can be classified into two types: acute renal failure (ARF) and chronic renal failure (CRF).
Acute kidney injury develops suddenly and can be caused by pre-renal causes (e.g., hypovolemia, shock), intrinsic renal causes (e.g., acute tubular necrosis), or post-renal causes (e.g., urinary obstruction). In contrast, chronic renal failure progresses gradually over time and is often...
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Pathophysiology of Diabetes01:20

Pathophysiology of Diabetes

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Diabetes mellitus is a chronic metabolic disorder characterized by hyperglycemia. The four categories of diabetes are type 1 diabetes, type 2 diabetes, other specific types of diabetes, and gestational diabetes.
Type 1 diabetes is characterized by autoimmune-mediated destruction of pancreatic β cells, with environmental factors potentially triggering this process in genetically susceptible individuals. Despite many not having a family history, certain genes increase susceptibility,...
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Preventive Healthcare Services01:30

Preventive Healthcare Services

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Preventive healthcare services keep people healthy via frequent check-ups, screening, and counseling. They primarily aid in disease prevention rather than treating an acute or chronic illness. Preventive treatment also keeps individuals productive and energetic, allowing them to work well into their retirement years. Examples of preventive care services include:
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Updated: Jun 27, 2025

Comparative Proteomic Analysis of Whole Kidney, Medulla, and Cortical Tubules in Diabetic Pathogenesis of Kidney Injury in Mice
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Comparative Proteomic Analysis of Whole Kidney, Medulla, and Cortical Tubules in Diabetic Pathogenesis of Kidney Injury in Mice

Published on: May 2, 2025

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Diabetic Kidney Disease Prevention Care Model Development.

Nuha A ElSayed1,2, Raveendhara R Bannuru1, George Bakris3

  • 1American Diabetes Association, Alexandria, VA.

Clinical Diabetes : a Publication of the American Diabetes Association
|May 2, 2024
PubMed
Summary
This summary is machine-generated.

Diabetic kidney disease (DKD) affects over a third of people with diabetes, increasing risks for kidney failure and cardiovascular disease (CVD). A comprehensive model is presented to prevent and manage DKD through multifaceted interventions and interdisciplinary care.

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Area of Science:

  • Nephrology
  • Endocrinology
  • Public Health

Background:

  • Diabetic kidney disease (DKD) is a major complication of diabetes, significantly increasing risks for kidney failure, cardiovascular disease (CVD), and mortality.
  • Over one-third of individuals with diabetes are affected by DKD, highlighting a critical unmet need for effective prevention and management strategies.

Purpose of the Study:

  • To present the DKD Prevention Model developed by an expert panel convened by the American Diabetes Association.
  • To provide a comprehensive framework for the prevention and treatment of DKD, addressing screening, diagnosis, and management.

Main Methods:

  • Convening an expert panel to develop a multifaceted DKD Prevention Model.
  • Incorporating elements of self-management education, lifestyle optimization, pharmacological intervention, CVD prevention, and psychosocial support.
  • Defining roles for interdisciplinary health care professionals and outlining community engagement strategies.

Main Results:

  • The developed DKD Prevention Model offers a holistic approach to DKD management.
  • The model includes updated screening guidelines, diagnostic tools, and management strategies.
  • It emphasizes the importance of interdisciplinary collaboration and community involvement in DKD prevention and care.

Conclusions:

  • A comprehensive, multifaceted approach is essential for mitigating the onset and progression of DKD.
  • The DKD Prevention Model provides a structured framework for healthcare professionals to improve patient outcomes.
  • Future research and policy are needed to further advance DKD prevention and management.