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Zaib Un Nisa Mughal1, Bisma Ahmed1, Burhanuddin Sohail Rangwala1

  • 1Department of Medicine, Jinnah Sindh Medical University, Karachi, Sindh, Pakistan.

Annals of Medicine and Surgery (2012)
|May 2, 2024
PubMed
Abstract

No abstract available in PubMed .

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Receptor tyrosine kinase inhibitors (TKIs) and calcium channel blockers (CCBs) are two critical categories of drugs employed in the treatment of pulmonary artery hypertension (PAH). PAH is a disease that causes high blood pressure in the pulmonary arteries, resulting in chest pain, fatigue, and shortness of breath.
TKIs, such as imatinib (Gleevec), are particularly effective in tackling the growth and mitogenic factors that become upregulated in PAH patients. These factors contribute to the...
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