Aortitis and Recurrent Staphylococcus aureus Bacteremia

Andreia Coutinho1, Inês De Albuquerque Monteiro1, Sofia Festa1

  • 1Internal Medicine, Centro Hospitalar do Médio Ave, Santo Tirso, PRT.

Cureus
|May 2, 2024
PubMed

Insights

Infectious aortitis, a rare condition, demands consideration with persistent bacteremia. This case highlights Staphylococcus aureus causing aortitis and aneurysm, even with treatment, suggesting a potential link to pancreatic cancer.

Area of Science:

  • Cardiovascular Medicine
  • Infectious Diseases
  • Oncology

Background:

  • Infectious aortitis is a rare but serious condition with high mortality rates.
  • It should be suspected in patients with persistent bacteremia, particularly when endocarditis is absent.

Observation:

  • A case of a woman with methicillin-sensitive Staphylococcus aureus (MSSA) infectious aortitis is presented.
  • The condition complicated into a mycotic aneurysm with recurrent bacteremia, persisting despite appropriate antibiotic therapy.

Findings:

  • Recurrent bacteremia occurred despite targeted antibiotic treatment for MSSA.
  • A probable diagnosis of malignant pancreatic neoplasia was noted concurrently.

Implications:

  • This case underscores the importance of considering infectious aortitis in unexplained persistent bacteremia.
  • The potential contribution of an underlying malignancy, such as pancreatic cancer, to recurrent bacteremia warrants further investigation.

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