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Published on: February 3, 2014
Echocardiographic Assessment of Right Ventricular Function in Patients With Liver Cirrhosis
Augustine A Enenche1,2, Anthony G Kweki3, Henry O Aiwuyo4
1Internal Medicine, Jos University Teaching Hospital, Jos, NGA.
Insights
Liver cirrhosis frequently causes heart problems, specifically right ventricular dysfunction. This study found a high prevalence of both systolic and diastolic dysfunction in these patients, highlighting the need for cardiac assessment.
Area of Science:
- Cardiology
- Hepatology
- Internal Medicine
Background:
- Liver cirrhosis is a common endpoint of chronic liver disease, leading to significant cardiovascular morbidity and mortality.
- Cardiac abnormalities, particularly in the right ventricle, are detectable via echocardiography in cirrhotic patients.
- Early identification and management of cardiac dysfunction can improve outcomes for liver cirrhosis patients.
Purpose of the Study:
- To determine the prevalence of right ventricular systolic dysfunction in liver cirrhosis patients.
- To ascertain the prevalence of right ventricular diastolic dysfunction in liver cirrhosis patients.
Main Methods:
- A hospital-based cross-sectional study involving 210 adult liver cirrhosis patients.
- Echocardiography and electrocardiography were utilized to assess right ventricular function.
- Data collection occurred over a one-year period within gastroenterology units.
Main Results:
- Right ventricular hypertrophy was observed in 44.8% of participants, with 3.8% showing dilatation.
- Right ventricular systolic dysfunction was detected in 17.1% (by TAPSE) and 51.4% (by FAC).
- Diastolic dysfunction was prevalent in 61% of patients, with Grade 2 being the most common.
Conclusions:
- A high prevalence of right ventricular systolic dysfunction exists in liver cirrhosis patients.
- Right ventricular diastolic dysfunction is also highly prevalent among individuals with liver cirrhosis.
- These findings underscore the importance of cardiac evaluation in the management of liver cirrhosis.
Background:
In patients with chronic liver disease, the common endpoint of its course is liver cirrhosis which is a cause of cardiovascular morbidity and mortality. These abnormalities in the cardiovascular system, especially the heart, can be detected by echocardiography. Identifying and acting on these abnormalities can have an impact on their management thereby reducing morbidity and mortality of patients with liver cirrhosis. The aim of this study was to determine the prevalence of right ventricular systolic and diastolic dysfunction in liver cirrhosis patients.
Methods And Materials:
A hospital-based cross-sectional study was conducted among adult patients of the gastroenterology unit (ward and clinic) diagnosed with liver cirrhosis. A total of 243 patients were recruited and 210 were evaluated for this study. This study was carried out over one year. Cardiology studies, including electrocardiography and echocardiography, were conducted on patients to assess right ventricular function.
Results:
Among the participants, 44.8% had right ventricular hypertrophy and 3.8% had right ventricular dilatation. Using Tricuspid Annular Plane Systolic Excursion (TAPSE), 17.1% were found to have right ventricular systolic dysfunction and 51.4% had systolic dysfunction using FAC. Diastolic dysfunction was found in 61% of the participants and grade 2 diastolic dysfunction was the commonest.
Conclusion:
From this study, a high prevalence of right ventricular systolic and diastolic dysfunction was recorded among patients with liver cirrhosis.
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