Echocardiographic Assessment of Right Ventricular Function in Patients With Liver Cirrhosis

Augustine A Enenche1,2, Anthony G Kweki3, Henry O Aiwuyo4

  • 1Internal Medicine, Jos University Teaching Hospital, Jos, NGA.

Cureus
|May 2, 2024
PubMed

Insights

Liver cirrhosis frequently causes heart problems, specifically right ventricular dysfunction. This study found a high prevalence of both systolic and diastolic dysfunction in these patients, highlighting the need for cardiac assessment.

Area of Science:

  • Cardiology
  • Hepatology
  • Internal Medicine

Background:

  • Liver cirrhosis is a common endpoint of chronic liver disease, leading to significant cardiovascular morbidity and mortality.
  • Cardiac abnormalities, particularly in the right ventricle, are detectable via echocardiography in cirrhotic patients.
  • Early identification and management of cardiac dysfunction can improve outcomes for liver cirrhosis patients.

Purpose of the Study:

  • To determine the prevalence of right ventricular systolic dysfunction in liver cirrhosis patients.
  • To ascertain the prevalence of right ventricular diastolic dysfunction in liver cirrhosis patients.

Main Methods:

  • A hospital-based cross-sectional study involving 210 adult liver cirrhosis patients.
  • Echocardiography and electrocardiography were utilized to assess right ventricular function.
  • Data collection occurred over a one-year period within gastroenterology units.

Main Results:

  • Right ventricular hypertrophy was observed in 44.8% of participants, with 3.8% showing dilatation.
  • Right ventricular systolic dysfunction was detected in 17.1% (by TAPSE) and 51.4% (by FAC).
  • Diastolic dysfunction was prevalent in 61% of patients, with Grade 2 being the most common.

Conclusions:

  • A high prevalence of right ventricular systolic dysfunction exists in liver cirrhosis patients.
  • Right ventricular diastolic dysfunction is also highly prevalent among individuals with liver cirrhosis.
  • These findings underscore the importance of cardiac evaluation in the management of liver cirrhosis.
Abstract

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