Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Organic Compounds03:02

Organic Compounds

45.9K
All living things are formed mostly of carbon compounds called organic compounds. The category of organic compounds includes both natural and synthetic compounds that contain carbon. Although a single, precise definition has yet to be identified by the chemistry community, most agree that a defining trait of organic molecules is the presence of carbon as the principal element, bonded to hydrogen and other carbon atoms. However, some carbon-containing compounds such as carbonates, cyanides, and...
45.9K
Constitutional Isomers of Alkanes02:18

Constitutional Isomers of Alkanes

18.7K
Organic compounds of the same molecular formula can have different structural formulas called constitutional isomers, and the phenomenon is known as constitutional isomerism. Alkanes with four or more carbons showing multiple structures with the same molecular formula thereby exhibit constitutional isomerism.
The linear isomer of an alkane is prefixed by the term “n”; hence a linear isomer of pentane is known as n-pentane. Based on the type of branching, some of the...
18.7K
Conformations of Ethane and Propane02:18

Conformations of Ethane and Propane

13.9K
In an organic molecule, free rotation about the carbon-carbon single bond results in energetically different conformers of the molecule. Due to this rotation, called the internal rotation, ethane has two major conformations — staggered and eclipsed.
Staggered conformation is a low energy and more stable conformation with the C-H bonds on the front carbon placed at 60°dihedral angles relative to the C-H bonds on the back carbon, leading to a reduced torsional strain. In staggered...
13.9K
Conformations of Cycloalkanes02:29

Conformations of Cycloalkanes

12.2K
Adolf von Baeyer attempted to explain the instabilities of small and large cycloalkane rings using the concept of angle strain — the strain caused by the deviation of bond angles from the ideal 109.5° tetrahedral value for sp3  hybridized carbons. However, while cyclopropane and cyclobutane are strained, as expected from their highly compressed bond angles, cyclopentane is more strained than predicted, and cyclohexane is virtually strain-free. Hence, Baeyer’s theory that...
12.2K
Radical Chain-Growth Polymerization: Chain Branching01:17

Radical Chain-Growth Polymerization: Chain Branching

1.8K
The skeletal structure of polymers synthesized via radical polymerization is always branched. For example, the polymerization of ethylene by radical polymerization results in a low-density grade of polyethylene with a heavily branched skeletal structure. Here, the radical site abstracts hydrogen from the growing chain, and the radical site shifts from the end (a primary carbon center) to anywhere within the growing chain (a secondary carbon center). Consequently, the part of the chain from the...
1.8K
Olefin Metathesis Polymerization: Overview01:13

Olefin Metathesis Polymerization: Overview

1.8K
Recently, the development of olefin metathesis polymerization advanced the field of polymer synthesis. Simply put, the reorganization of substituents on their double bonds between two olefins in the presence of a catalyst is known as the olefin metathesis reaction. The use of metathesis reaction for polymer synthesis is called olefin metathesis polymerization.
Ruthenium-based Grubbs catalyst is the most commonly used catalyst for olefin metathesis polymerization. Grubbs catalyst consists of a...
1.8K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Photo-Responsive Supramolecular Nanopesticides via Ternary Host-Guest Complexes of Cucurbit[8]uril/Paraquat/Azobenzene on Mesoporous Silica Nanoparticles.

Chemistry (Weinheim an der Bergstrasse, Germany)·2026
Same author

Tyrosinase Driven-Intracellular Polymerization of a Porphyrin Derivative Induced Immunogenic Death of Melanoma Cells and Strengthened Photodynamic Therapy.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)·2026
Same author

An Exclusive Synthesis of Macrocyclic Trimer over Polymers.

Organic letters·2026
Same author

Cyclicurilarenes: Hybridizing Bambusurils with Macrocyclic Arenes.

Organic letters·2026
Same author

In Situ Synthesis of Covalent Organic Frameworks Inside Cells for Triggering Ferroptosis and Immunotherapy.

Advanced materials (Deerfield Beach, Fla.)·2026
Same author

Tough transparent glass ceramics for multi-mode programmable dynamic tunable persistent luminescence via phase engineering.

Nature communications·2026

Related Experiment Video

Updated: May 2, 2026

Amide Coupling Reaction for the Synthesis of Bispyridine-based Ligands and Their Complexation to Platinum as Dinuclear Anticancer Agents
07:20

Amide Coupling Reaction for the Synthesis of Bispyridine-based Ligands and Their Complexation to Platinum as Dinuclear Anticancer Agents

Published on: May 28, 2014

14.0K

Pillarurilarenes: Glycoluril-Expanded Pillararenes.

Chao Ruan1,2, Zhijin Li1, Wenhao Lin1

  • 1Key Laboratory of Mesoscopic Chemistry of MOE, Jiangsu Key Laboratory of Advanced Organic Materials, School of Chemistry and Chemical Engineering, Nanjing University, Nanjing 210023, China.

Organic Letters
|May 2, 2024
PubMed
Summary
This summary is machine-generated.

New pillarurilarenes (PURA) were synthesized by incorporating glycoluril units into pillararene structures. This modification introduces polarized protons, enabling further chemical reactions and anion binding applications.

More Related Videos

Synthesis and Characterization of Functionalized Metal-organic Frameworks
11:27

Synthesis and Characterization of Functionalized Metal-organic Frameworks

Published on: September 5, 2014

48.1K
Author Spotlight: In Vitro Hydrogel Model for Glioblastoma Microenvironment Study
10:44

Author Spotlight: In Vitro Hydrogel Model for Glioblastoma Microenvironment Study

Published on: September 22, 2023

1.4K

Related Experiment Videos

Last Updated: May 2, 2026

Amide Coupling Reaction for the Synthesis of Bispyridine-based Ligands and Their Complexation to Platinum as Dinuclear Anticancer Agents
07:20

Amide Coupling Reaction for the Synthesis of Bispyridine-based Ligands and Their Complexation to Platinum as Dinuclear Anticancer Agents

Published on: May 28, 2014

14.0K
Synthesis and Characterization of Functionalized Metal-organic Frameworks
11:27

Synthesis and Characterization of Functionalized Metal-organic Frameworks

Published on: September 5, 2014

48.1K
Author Spotlight: In Vitro Hydrogel Model for Glioblastoma Microenvironment Study
10:44

Author Spotlight: In Vitro Hydrogel Model for Glioblastoma Microenvironment Study

Published on: September 22, 2023

1.4K

Area of Science:

  • Supramolecular Chemistry
  • Organic Synthesis
  • Macrocyclic Chemistry

Background:

  • Pillararenes are a class of macrocyclic hosts with a tunable cavity.
  • Expanding pillararene structures with different units can alter their properties and functionalities.
  • Glycoluril units offer unique electronic and binding characteristics.

Purpose of the Study:

  • To synthesize novel glycoluril-expanded pillararenes, termed pillarurilarenes (PURA).
  • To investigate the structural and electronic properties of PURA, focusing on the impact of glycoluril incorporation.
  • To explore the potential of PURA for derivatization and CH-anion binding.

Main Methods:

  • Fragment coupling macrocyclization strategy for PURA synthesis.
  • Single-crystal X-ray diffraction for structural elucidation of pillar[2]uril[4]arene and pillar[1]uril[4]arene.
  • 1H nuclear magnetic resonance (NMR) spectroscopy and density functional theory (DFT) calculations to analyze structural and electronic properties.

Main Results:

  • Successful synthesis of pillarurilarenes (PURA) incorporating glycoluril and dialkoxybenzene units.
  • PURA exhibits polarized equatorial methine protons, facilitating derivatization and CH-anion binding.
  • Structural analysis revealed an inward orientation of the glycoluril units within the macrocycle.

Conclusions:

  • Glycoluril expansion provides a new avenue for modifying pillararene frameworks.
  • The unique properties of PURA open possibilities for advanced host-guest chemistry and materials science.
  • This research establishes a foundation for incorporating non-aromatic rings into pillararene structures.