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Updated: Jun 27, 2025

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Sphenopalatine artery pseudoaneurysm masquerading as a second primary maxillary carcinoma
William Ansley1, Smile Kajal2,3, Sabrina Brar4
1St George's, University of London, Cranmer Terrace, London, SW17 0RE, UK.
Summary
A rare case of sphenopalatine artery pseudoaneurysm mimicked a second maxillary carcinoma in a patient with a history of sinonasal malignancy. Endovascular embolization successfully treated the pseudoaneurysm, resolving recurrent epistaxis.
Area of Science:
- Otolaryngology
- Interventional Radiology
- Oncology
Background:
- Maxillary sinus carcinomas are typically diagnosed at advanced stages.
- Recurrence as a contralateral primary malignancy is exceptionally rare.
- Sphenopalatine artery (SPA) pseudoaneurysms can present with epistaxis.
Observation:
- A 90-year-old male with prior right maxillary sinus cancer presented with recurrent epistaxis.
- Radiology revealed a left maxillary sinus mass suspicious for malignancy.
- Intraoperative bleeding necessitated a change in management strategy.
Findings:
- Diagnostic angiography identified a sphenopalatine artery pseudoaneurysm.
- The pseudoaneurysm was successfully treated with endovascular embolization.
- This condition mimicked a secondary maxillary sinus malignancy.
Implications:
- Sphenopalatine artery pseudoaneurysms are a critical differential diagnosis for recurrent epistaxis in patients with sinonasal cancer history.
- Endovascular embolization offers a successful management option for SPA pseudoaneurysms.
- Accurate diagnosis prevents unnecessary aggressive surgical intervention for sinonasal masses.
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