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Author Spotlight: 3D Movement Assessment of Maxillary Posterior Teeth in Clear Aligner Treatment
Published on: February 23, 2024
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Clear aligner's adverse effects: A systematic review protocol
Cintia Ronchi Lemos1, Marianella Aguilar Ventura Fadel1, Helena Polmann1
1Brazilian Centre for Evidence-Based Research (COBE), Department of Dentistry, Federal University of Santa Catarina (UFSC), Florianópolis, Brazil.
Plos One
|May 2, 2024
Summary
This systematic review examines the adverse effects of clear aligners, a popular alternative to traditional braces. It synthesizes published data to identify potential negative outcomes associated with this orthodontic treatment.
Area of Science:
- Orthodontics
- Dental Materials
Background:
- Clear aligners are increasingly preferred over traditional braces for malocclusion correction.
- Advantages include aesthetics, convenience, and reduced oral irritation.
- Potential adverse effects of clear aligners require comprehensive assessment.
Purpose of the Study:
- To conduct a systematic review of published literature on adverse/negative effects of clear aligners.
- To investigate the frequency and nature of these adverse effects.
- To identify limitations of clear aligner therapy.
Main Methods:
- Systematic review with potential meta-analysis.
- Inclusion of studies reporting adverse/negative effects in clear aligner users.
- Two-stage screening by independent reviewers (title/abstract, then full text).
Main Results:
- Synthesis of findings from eligible studies.
- Narrative description of adverse effects and their frequency.
- Meta-analysis if data permits.
Conclusions:
- The review will provide insights into the adverse effects of clear aligner therapy.
- Findings will help illuminate inherent limitations of aligner treatments.
- This research addresses a gap in the literature regarding clear aligner safety.

