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Related Experiment Video

Updated: Jun 27, 2025

A Simple Approach to Induce Experimental Autoimmune Neuritis in C57BL/6 Mice for Functional and Neuropathological Assessments

A Simple Approach to Induce Experimental Autoimmune Neuritis in C57BL/6 Mice for Functional and Neuropathological Assessments

Published on: November 9, 2017

Focal inflammatory neuropathies.

Rocio Vazquez Do Campo¹, P James B Dyck²

¹Department of Neurology, University of Alabama at Birmingham, Birmingham, AL, United States.

Handbook of Clinical Neurology

|May 2, 2024

Summary

This summary is machine-generated.

This chapter reviews focal neuropathies caused by autoimmune and inflammatory conditions. It covers the presentation, diagnosis, and treatment of various focal nerve disorders.

Keywords:

Brachial plexopathy Focal CIDP Focal neuropathy Infectious neuropathy Inflammatory neuropathy Microvasculitis Postsurgical neuropathy Radiculoplexus neuropathy Sarcoid neuropathy

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Area of Science:

Neurology
Immunology
Pathology

Background:

Focal neuropathies involve specific nerve roots, plexus, or peripheral nerves.
Autoimmune and inflammatory mechanisms are key contributors to these focal neurological deficits.

Purpose of the Study:

To review the clinical presentation, diagnosis, and treatment of focal neuropathies.
To consolidate information on neuropathies associated with autoimmune, inflammatory, infectious, and neoplastic processes.

Main Methods:

Literature review of focal neuropathies.
Analysis of clinical presentations, diagnostic criteria, and therapeutic strategies.
Categorization based on underlying etiology (autoimmune, inflammatory, infectious).

Main Results:

Detailed review of focal autoimmune demyelinating neuropathies.
Discussion of focal nonsystemic vasculitic disorders including diabetic and nondiabetic radiculoplexus neuropathies, postsurgical inflammatory neuropathy, and neuralgic amyotrophy.
Examination of focal neuropathies linked to sarcoidosis, bacterial, and viral infections.

Conclusions:

Accurate diagnosis and timely treatment are crucial for managing focal neuropathies.
Understanding the diverse etiologies is essential for effective patient management.
Further research into specific inflammatory and autoimmune neuropathies is warranted.