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A Rare Occurrence of Spontaneous Coronary Artery Dissection in Elderly: Diagnostic Challenges and Clinical
Ahmad W Haddad1, Wassim Abouzeid1, Noreen Mirza1
1Internal Medicine, Saint Michael's Medical Center, Newark, USA.
Insights
This case study presents a rare instance of spontaneous coronary artery dissection (SCAD) in a 65-year-old female, highlighting atypical presentations of this condition. The findings emphasize the need to consider SCAD in older women, even without typical risk factors.
Area of Science:
- Cardiology
- Vascular Biology
Background:
- Spontaneous coronary artery dissection (SCAD) involves a tear in the coronary artery wall, leading to potential blood flow obstruction and myocardial ischemia.
- SCAD is increasingly recognized in acute coronary syndromes, especially in young females with few traditional atherosclerotic risk factors.
Observation:
- A 65-year-old female with hypertension, hyperlipidemia, asthma, and chronic kidney disease presented with chest pain and elevated troponin levels.
- Coronary angiography revealed spontaneous dissection of the left anterior descending artery (LAD).
- The patient also exhibited imaging findings consistent with takotsubo cardiomyopathy.
Findings:
- This case represents a rare occurrence of SCAD in an older female demographic, challenging typical patient profiles.
- The patient's presentation lacked common SCAD predisposing factors like youth, pregnancy, or significant stressors.
- The co-occurrence of SCAD and takotsubo cardiomyopathy suggests a complex and potentially related cardiac pathology.
Implications:
- Reporting rare SCAD cases in atypical demographics is crucial to prevent diagnostic oversight.
- Clinicians should consider SCAD in older women presenting with acute coronary syndromes, irrespective of traditional risk factors.
- Further research into the complex interplay between SCAD and takotsubo cardiomyopathy is warranted.
Abstract:
Spontaneous coronary artery dissection (SCAD) is the ripping of the epicardial coronary artery wall without any trauma, coronary procedures, or rupture of atherosclerotic plaque. Intimal rip, intramural hematoma, and false lumen formation are the hallmarks of this disease, which may result in coronary blood flow obstruction and myocardial ischemia. The role of SCAD in acute coronary syndrome (ACS), and sudden death has come to light more and more, particularly in young females and those with few typical atherosclerotic risk factors. This study details a 65-year-old female with a history of hypertension, hyperlipidemia, asthma, and chronic kidney disease who presented with severe chest pain and elevated troponin levels. Upon investigation, spontaneous dissection of the left anterior descending artery (LAD) involving its mid and distal segments was identified. The present case highlights a rare occurrence of spontaneous coronary artery dissection (SCAD) in a demographic typically unaffected by the condition - females aged 65 years and over. The atypical presentation underscores the importance of reporting such cases to prevent oversight. This patient's case is particularly noteworthy as it deviates from the typical predisposing factors associated with SCAD, such as youth, pregnancy, or stressors. Additionally, the case is unique in that it presented both SCAD and imaging findings consistent with takotsubo cardiomyopathy, suggesting a complex cardiac pathology deserving of further study and consideration.
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