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Early diagnosis and aggressive surgical resection matters to cure rhinocerebral mucormycosis: Six case reports

Maximiliano Repetto1, David González-Quintanilla2, Ana Alarcón3

  • 1Department of Oral and Maxillofacial Surgery, Hospital Hernán Henriquez Aravena, Manuel Montt 115, Temuco, Chile.

Journal of Stomatology, Oral and Maxillofacial Surgery
|May 3, 2024
PubMed

Insights

Early diagnosis and treatment are crucial for rhino-cerebral mucormycosis (RM), a dangerous fungal infection in immunocompromised patients. Prompt antifungal therapy, metabolic control, and surgery significantly improve outcomes and reduce high mortality rates.

Area of Science:

  • Medicine
  • Infectious Diseases
  • Mycology

Background:

  • Rhino-cerebral mucormycosis (RM) is a rare, opportunistic fungal infection.
  • It primarily affects immunocompromised individuals and those with metabolic disorders like Diabetes Mellitus.
  • RM is characterized by rapid vascular infiltration, thrombosis, and tissue necrosis, leading to high mortality (23.6-60%).
Keywords:
AntifungalMucormycosisNecrosisParanasal sinusesRhino-cerebralSurgical debridement

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