Children and the Opioid Crisis: We Can Make a Difference

Lisa Allison Herbinger1

  • 1Department of Nurse Anesthesia, Samford University, Birmingham, AL; Department of Anesthesia, Children's of Alabama, Birmingham, AL.

Insights

Opioid-sparing and opioid-free pain management in children offers adequate pain relief with fewer side effects. Individualized plans are crucial for safe and effective perioperative care, supporting the fight against the opioid crisis.

Area of Science:

  • Pediatric Anesthesiology
  • Pain Management
  • Public Health

Background:

  • Opioid use in children presents risks, including adverse events and contribution to the opioid crisis.
  • Effective perioperative pain management is essential for pediatric surgical outcomes.
  • Balancing pain control with opioid risks requires careful consideration.

Purpose of the Study:

  • To highlight the importance of opioid-sparing and opioid-free strategies in pediatric perioperative pain management.
  • To emphasize the need for individualized pain management plans in children.
  • To advocate for a comprehensive understanding of pain management options.

Main Methods:

  • Review of current literature on pediatric pain management.
  • Discussion of risks and benefits of opioids, nonopioid adjuncts, and regional anesthesia.
  • Ethical considerations in pediatric pain management.

Main Results:

  • Opioid-sparing and opioid-free approaches can provide adequate analgesia in children.
  • These strategies reduce the risk of opioid-related adverse events.
  • Individualized patient evaluation is key to successful pain management.

Conclusions:

  • Perioperative practitioners have an obligation to utilize opioid-sparing/opioid-free strategies for optimal pediatric outcomes.
  • A thorough knowledge of pain management modalities and ethical principles is vital.
  • Implementing these strategies contributes to combating the opioid crisis.

Related Concept Videos

Opioid Analgesics: Morphine and Other Natural Cogeners01:20

Opioid Analgesics: Morphine and Other Natural Cogeners

Opioids are a class of drugs that mimic endogenous opioid peptides and act on opioid receptors, and help in pain relief. These compounds are classified as natural, synthetic, or semi-synthetic. Natural opioids, like morphine, codeine, and thebaine, are derived from the opium poppy plant (Papaver somniferum or Papaver album) and are termed opiates. Synthetic opioids are artificial, while semi-synthetic opioids combine natural and synthetic compounds. Morphine, a prototypical opioid, possesses a...
242
Opioid Analgesics: Synthetic and Semisynthetic Opioids01:15

Opioid Analgesics: Synthetic and Semisynthetic Opioids

Synthetic and semisynthetic opioids are pivotal in pain management and tackling opioid addiction. Semisynthetic opioids, including morphinans (morphine derivatives), oxycodone, oxymorphone, hydrocodone, and hydromorphone, have improved pharmacokinetic profiles compared to morphine. Additionally, heroin and 6-MAM (6-Monoacetylmorphine) show better CNS penetration than morphine due to heightened lipid solubility. Hydromorphone, a potent opioid, undergoes hepatic metabolism to form the active...
287
Analgesia and Pain Management01:25

Analgesia and Pain Management

Pain is critical to various clinical pathologies, provoking an urgent need for effective management. Pain, whether acute or chronic, is a complex neurochemical process. Its alleviation depends on the type, with nonopioid analgesics effective for mild to moderate pain, such as musculoskeletal or inflammatory pain, while neuropathic pain responds best to anticonvulsants, tricyclic antidepressants, or serotonin/norepinephrine reuptake inhibitors. For severe acute or chronic pain, opioids may be...
585
Prescription, Nonprescription and Orphan Drugs01:02

Prescription, Nonprescription and Orphan Drugs

Prescription drugs require a prescription from a medical practitioner and can only be obtained from a pharmacy. They have many applications, including treating pain, anxiety, and hypertension.
The misuse and addiction to prescription drugs is a growing problem that can affect people of all age groups, specifically teenagers. This can happen when prescription medications are used in ways not intended by the prescriber, such as taking someone else's prescription or using medication for...
722
Drugs Affecting GI Tract Motility: Opioids as Antidiarrheal Agents01:17

Drugs Affecting GI Tract Motility: Opioids as Antidiarrheal Agents

Diarrhea, a condition marked by frequent loose or watery bowel movements, can be triggered by multiple factors such as viral or bacterial infections, food intolerances, anxiety, medications, and digestive disorders. Symptoms may include abdominal pain, bloating, nausea, and cramping. Severe or prolonged diarrhea can lead to complications like electrolyte imbalances, malnutrition, and dehydration if left untreated.
Opioids, widely used antidiarrheal agents, mitigate diarrhea by slowing down...
193
Opioid Receptors: Overview01:22

Opioid Receptors: Overview

Opioid receptors, including the mu (μ, MOR), delta (δ, DOR), and kappa (κ, KOR) types, belong to the rhodopsin family of G protein-coupled receptors. These receptors are located throughout the central and peripheral nervous systems and in non-neuronal tissues such as macrophages and astrocytes. Opioid receptor ligands can be categorized into agonists or antagonists. Highly selective agonists include [d-Ala2, MePhe4, Gly(ol)5]-enkephalin or DAMGO for MOR, [D-Pen2,...
761