Overview of the Global and US Burden of Preterm Birth

Victoria C Ward1, Anne Cc Lee2, Steven Hawken3

  • 1Department of Pediatrics, Stanford University School of Medicine, 291 Campus Drive, Li Ka Shing Building, Stanford, CA 94305, USA.

PubMed

Insights

Preterm birth (PTB) remains a global health challenge with no significant change in rates since 2010. Addressing PTB is critical, especially in Africa and Asia, due to persistent racial disparities and limited prevention solutions.

Area of Science:

  • Neonatal Health
  • Global Public Health
  • Epidemiology

Background:

  • Preterm birth (PTB) is the primary cause of infant morbidity and mortality worldwide.
  • Accurate PTB prevalence estimation is challenging due to inconsistent dating methods and data limitations.
  • Significant disparities in PTB exist, particularly concerning racial inequalities in the United States.

Purpose of the Study:

  • To analyze the global prevalence of preterm birth.
  • To highlight regional disparities in PTB rates and associated mortality.
  • To underscore the need for further research into prematurity prevention.

Main Methods:

  • Utilized global data to estimate preterm birth rates for 2020.
  • Analyzed trends in PTB prevalence from 2010 to 2020.
  • Examined geographical distribution of prematurity-related deaths.

Main Results:

  • The global preterm birth rate in 2020 was 9.9%, showing no significant change from 2010.
  • Africa and Asia account for 81% of all prematurity-related deaths.
  • The US reported a 10.5% PTB rate in 2021, with notable racial disparities.

Conclusions:

  • Preterm birth remains a critical global health issue requiring urgent attention.
  • Targeted interventions are needed in high-burden regions like Africa and Asia.
  • Further research is essential to identify effective prematurity prevention strategies.

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