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Regression Toward the Mean01:52

Regression Toward the Mean

Regression toward the mean (“RTM”) is a phenomenon in which extremely high or low values—for example, and individual’s blood pressure at a particular moment—appear closer to a group’s average upon remeasuring. Although this statistical peculiarity is the result of random error and chance, it has been problematic across various medical, scientific, financial and psychological applications. In particular, RTM, if not taken into account, can interfere when researchers try to extrapolate results...

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Computational Approaches for Predicting Preterm Birth and Newborn Outcomes.

David Seong1, Camilo Espinosa2, Nima Aghaeepour3

  • 1Immunology Program, Stanford University School of Medicine, 300 Pasteur Drive, Grant S280, Stanford, CA 94305-5117, USA; Medical Scientist Training Program, Stanford University School of Medicine, 300 Pasteur Drive, Grant S280, Stanford, CA 94305-5117, USA; Department of Microbiology and Immunology, Stanford University School of Medicine, 300 Pasteur Drive, Grant S280, Stanford, CA 94305-5117, USA; Department of Anesthesiology, Perioperative and Pain Medicine, Stanford University, School of Medicine, 300 Pasteur Drive, Grant S280, Stanford, CA 94305-5117, USA.

Clinics in Perinatology
|May 5, 2024
PubMed
Summary

Artificial intelligence (AI) can analyze complex data to improve understanding of preterm birth (PTB). This review explores AI

Keywords:
Computational modelingMultimodalNeonatal outcomesPreterm birth

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Area of Science:

  • Reproductive Health
  • Medical Informatics
  • Artificial Intelligence in Medicine

Background:

  • Preterm birth (PTB) is a major cause of infant mortality and morbidity.
  • Understanding PTB's multifactorial causes requires advanced analytical approaches.
  • Current predictive models for PTB and its morbidities need improvement.

Purpose of the Study:

  • To review the application of artificial intelligence (AI) in analyzing multimodal data for preterm birth research.
  • To highlight the potential of AI in gaining novel insights into the complex factors contributing to PTB.
  • To assess the integration of diverse data sources for enhanced PTB prediction and understanding.

Main Methods:

  • Review of studies utilizing AI for preterm birth analysis.
  • Analysis of AI applications across electronic health records (EHRs).
  • Examination of AI's role in interpreting biological omics data and social determinants of health (SDOH) metrics.

Main Results:

  • AI offers powerful tools for analyzing high-dimensional, multimodal datasets relevant to PTB.
  • Integration of EHR, omics, and SDOH data with AI can reveal complex PTB-associated patterns.
  • AI facilitates a deeper biological and clinical understanding of PTB.

Conclusions:

  • AI-driven analysis of multimodal data holds significant promise for advancing preterm birth research.
  • Improved predictive models and biological insights can be achieved through AI.
  • Future research should focus on leveraging AI for comprehensive PTB risk assessment and prevention strategies.