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Very Low-Dose Sublingual Ketamine for Borderline Personality Disorder and Treatment-Resistant Depression

Mitchell Liester1, Rachel Wilkenson2, Barry Patterson3

  • 1Department of Psychiatry, University of Colorado School of Medicine, Aurora, USA.

Cureus
|May 6, 2024
PubMed
Summary

Very low-dose sublingual ketamine shows promise for treating borderline personality disorder (BPD) and treatment-resistant depression (TRD). This case report suggests potential efficacy for these challenging psychiatric conditions.

Keywords:
ampa receptorborderline personality disorder (bpd)brain-derived neurotrophic factorglutamate dysregulationlow dose ketamineneuroplasticity enhancementtreatment resistant depression (trd)

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