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Published on: September 18, 2011
The Molecular Biological Mechanism of Hydrogen Therapy and Its Application in Spinal Cord Injury
Quan Hu1, Yingxiao Li2, Zhaochen Lin3
1Department of Neurosurgery, The Affiliated Taian City Central Hospital of Qingdao University, Tai'an City, Shandong, 271000, People's Republic of China.
Abstract:
Hydrogen, which is a novel biomedical molecule, is currently the subject of extensive research involving animal experiments and in vitro cell experiments, and it is gradually being applied in clinical settings. Hydrogen has been proven to possess anti-inflammatory, selective antioxidant, and antiapoptotic effects, thus exhibiting considerable protective effects in various diseases. In recent years, several studies have provided preliminary evidence for the protective effects of hydrogen on spinal cord injury (SCI). This paper provides a comprehensive review of the potential molecular biology mechanisms of hydrogen therapy and its application in treating SCI, with an aim to better explore the medical value of hydrogen and provide new avenues for the adjuvant treatment of SCI.
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