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Updated: May 5, 2026

Alternating Magnetic Field-Responsive Hybrid Gelatin Microgels for Controlled Drug Release
Published on: February 13, 2016
Sustained Release Studies of Metformin Hydrochloride Drug Using Conducting Polymer/Gelatin-Based Composite Hydrogels
Aleena Mir1, Wilbert J Fletcher2, Darlene K Taylor2
1Materials Research Laboratory, Department of Chemistry, Jamia Millia Islamia, New Delhi 110025, India.
None:
The present work highlights the synthesis and characterization of conducting polymer (CP)-based composite hydrogels with gelatin (GL-B) for their application as drug delivery vehicles. The spectral, morphological, and rheological properties of the synthesized hydrogels were explored, and morphological studies confirmed formation of an intense interpenetrating network. Rheological measurements showed variation in the flow behavior with the type of conducting polymer. The hydrogels showed a slow drug release rate of about 10 h due to the presence of the conducting polymer. The release kinetics were fitted in various mathematical models and were best fit in first order for PNA-, POPD-, and PANI-based GL-B hydrogels, and the PVDF/GL-B hydrogel was best fit in the zero-order models. The drug release was found to follow the order: POPD/GL-B > PANI/GL-B > PVDF/GL-B.
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