Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Relative Strengths of Conjugate Acid-Base Pairs02:29

Relative Strengths of Conjugate Acid-Base Pairs

45.7K
Brønsted-Lowry acid-base chemistry is the transfer of protons; thus, logic suggests a relation between the relative strengths of conjugate acid-base pairs. The strength of an acid or base is quantified in its ionization constant, Ka or Kb, which represents the extent of the acid or base ionization reaction. For the conjugate acid-base pair HA / A−, the ionization equilibrium equations and ionization constant expressions are
45.7K
Hydrogen Bonds00:26

Hydrogen Bonds

121.2K
Hydrogen bonds are weak attractions between atoms that have formed other chemical bonds. One of these atoms is electronegative, like oxygen, and has a partial negative charge. The other is a hydrogen atom that has bonded with another electronegative atom and has a partial positive charge.
Hydrogen Bonds Control the World!
Because hydrogen has very weak electronegativity when it binds with a strongly electronegative atom, such as oxygen or nitrogen, electrons in the bond are unequally shared....
121.2K
Introduction to Chemical Bonds01:01

Introduction to Chemical Bonds

8.0K
Chemical Bonds
The electrons of the outermost energy level determine the energetic stability of the atom and its tendency to form chemical bonds with other atoms. The innermost electron shell has a maximum capacity of two electrons, but the next two electron shells can each have a maximum of eight electrons. This is known as the octet rule, which states that, with the exception of the innermost shell, atoms are most stable energetically when they have eight electrons in their valence shell, the...
8.0K
Ions, Molecules, and Compounds01:23

Ions, Molecules, and Compounds

8.0K
Ions - When an atom participates in a chemical reaction that results in the donation or acceptance of one or more electrons, the atom becomes positively or negatively charged. This frequently happens for most atoms to have a full valence shell. This can happen either by gaining electrons to fill a shell that is more than half-full or by giving away electrons to empty a shell that is less than half-full, thereby leaving the next smaller electron shell as the new, full valence shell. An atom with...
8.0K
Buffer Systems in the Body01:19

Buffer Systems in the Body

798
Chemical buffers play a critical role in the body's regulation of pH levels. These systems contain one or more compounds that stabilize pH changes by neutralizing strong acids or bases. When pH levels drop, hydrogen ions bind to a weak base; when pH levels rise, hydrogen ions are released. This dynamic process helps maintain pH within a narrow and stable range essential for normal physiological function.
A typical buffer system in bodily fluids includes a weak acid and its corresponding...
798
Henderson-Hasselbalch Equation02:48

Henderson-Hasselbalch Equation

69.0K
The ionization-constant expression for a solution of a weak acid can be written as:
69.0K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

McArdle disease (Glycogen Storage Disease Type V) from an exercise physiology and biochemistry perspective: Important considerations for exercise and physical activity testing and data interpretation.

Sports medicine and health science·2026
Same author

D- and L-lactate dehydrogenase reactions increase pH to lactate production and decrease pH to pyruvate production.

Frontiers in molecular biosciences·2026
Same author

Lessons from history for <math><mrow><mover><mi>V</mi> <mo>˙</mo></mover> <msub><mi>O</mi> <mn>2</mn></msub></mrow></math> max and the <math><mrow><mover><mi>V</mi> <mo>˙</mo></mover> <msub><mi>O</mi> <mn>2</mn></msub></mrow></math> plateau, part 1, 1920 - 1961: original concepts were based on discontinuous exercise protocols.

Frontiers in physiology·2025
Same author

<math><mrow><mover><mi>V</mi> <mo>˙</mo></mover></mrow></math> O<sub>2</sub> linear-onset kinetics spanning steady- and non-steady-state exercise.

Frontiers in physiology·2025
Same author

Evaluating Airflow Sensor Methods: Precision in Indirect Calorimetry.

Scandinavian journal of medicine & science in sports·2024
Same author

The missing hydrogen ion, part-2: Where the evidence leads to.

Sports medicine and health science·2024

Related Experiment Video

Updated: Jun 27, 2025

Quantification of Hydrogen Concentrations in Surface and Interface Layers and Bulk Materials through Depth Profiling with Nuclear Reaction Analysis
14:11

Quantification of Hydrogen Concentrations in Surface and Interface Layers and Bulk Materials through Depth Profiling with Nuclear Reaction Analysis

Published on: March 29, 2016

26.7K

The missing hydrogen ion, Part-3: Science and the human flaws that compromise it.

Robert Robergs1, Bridgette O'Malley1, Sam Torrens1

  • 1School of Exercise and Nutrition Sciences, Queensland University of Technology, Kelvin Grove, Queensland, 4059, Australia.

Sports Medicine and Health Science
|May 6, 2024
PubMed
Summary

Scientific errors, like those in the lactic acidosis construct, are common due to flawed

Keywords:
AnomalyParadigmScienceScientific philosophy‘Normal’ science

More Related Videos

Millisecond Hydrogen/Deuterium-Exchange Mass Spectrometry for the Study of Alpha-Synuclein Structural Dynamics Under Physiological Conditions
08:40

Millisecond Hydrogen/Deuterium-Exchange Mass Spectrometry for the Study of Alpha-Synuclein Structural Dynamics Under Physiological Conditions

Published on: June 23, 2022

2.9K
Defining Hsp33's Redox-regulated Chaperone Activity and Mapping Conformational Changes on Hsp33 Using Hydrogen-deuterium Exchange Mass Spectrometry
10:24

Defining Hsp33's Redox-regulated Chaperone Activity and Mapping Conformational Changes on Hsp33 Using Hydrogen-deuterium Exchange Mass Spectrometry

Published on: June 7, 2018

8.7K

Related Experiment Videos

Last Updated: Jun 27, 2025

Quantification of Hydrogen Concentrations in Surface and Interface Layers and Bulk Materials through Depth Profiling with Nuclear Reaction Analysis
14:11

Quantification of Hydrogen Concentrations in Surface and Interface Layers and Bulk Materials through Depth Profiling with Nuclear Reaction Analysis

Published on: March 29, 2016

26.7K
Millisecond Hydrogen/Deuterium-Exchange Mass Spectrometry for the Study of Alpha-Synuclein Structural Dynamics Under Physiological Conditions
08:40

Millisecond Hydrogen/Deuterium-Exchange Mass Spectrometry for the Study of Alpha-Synuclein Structural Dynamics Under Physiological Conditions

Published on: June 23, 2022

2.9K
Defining Hsp33's Redox-regulated Chaperone Activity and Mapping Conformational Changes on Hsp33 Using Hydrogen-deuterium Exchange Mass Spectrometry
10:24

Defining Hsp33's Redox-regulated Chaperone Activity and Mapping Conformational Changes on Hsp33 Using Hydrogen-deuterium Exchange Mass Spectrometry

Published on: June 7, 2018

8.7K

Area of Science:

  • Explores the philosophy of science and its application in scientific research.
  • Focuses on the historical development of scientific constructs within sports medicine and health sciences.

Background:

  • The lactic acidosis construct serves as a case study for examining scientific errors.
  • Science is defined as a human behavior involving problem identification, method development, results acquisition, and interpretation.

Purpose of the Study:

  • To explain historical mistakes in the lactic acidosis construct using scientific philosophy.
  • To elucidate why scientists err, why science takes decades to correct errors, and the nature of science itself.

Main Methods:

  • Employs a historical research method.
  • Applies core principles from the philosophy of science.

Main Results:

  • Identifies 'normal science,' as described by Thomas Kuhn, as a dysfunctional form of scientific practice.
  • Highlights Karl Popper's critique of 'normal science' for deviating from fundamental scientific principles.
  • Reveals that errors in scientific research are more frequent than commonly expected.

Conclusions:

  • Errors in science, particularly in sports medicine and health sciences, are prevalent.
  • There is a critical need to enhance the education and training of scientists.
  • Preventing the pursuit of 'normal science' is essential to mitigate harm.